VP, Clinical Development — Cardiology Drug Program Lead

Kardigan, Inc.; Princeton, Northern (NJ, KY); Hybrid; USD 340,000 - 416,000; Full time

Job summary

Kardigan, Inc. is seeking a Vice President, Clinical Development to lead the Danicamtiv program. This role demands an MD or equivalent, with extensive experience directing clinical development in cardiology-focused biotechnology/pharmaceutical settings.

You will shape strategy, oversee protocol design, drive regulatory interactions, and mentor MDs within a high-growth biotech environment. You will liaise with the CMO, CEO, and executive team, present study progress, and represent Kardigan at

Qualifications

• MD (or equivalent medical degree); board certification and clinical practice experience in cardiology strongly preferred.
• 15+ years of experience in clinical development within biotechnology/pharmaceuticals; cardiomyopathy/heart failure focus preferred.
• Demonstrated experience serving as clinical lead for a major drug program through late-stage milestones.
• Strong understanding of cardiovascular trial designs, endpoints, and regulatory strategies.

Responsibilities

• Serve as Clinical Lead for the Danicamtiv program with end-to-end accountability for clinical strategy and execution, including protocol design and regulatory interactions.
• Lead the Danicamtiv Clinical Strategy Team with cross-functional leadership across development activities.
• Own clinical development plans and TPp development with input on indication and target product profile for Danicamtiv.
• Lead clinical decision-making based on emerging data, benefit–risk assessments, and evolving regulatory expectations.
• Act as primary clinical development point of contact for regulatory interactions, investigators, and key opinion leaders.
• Partner with Clinical Ops, Biometrics, Regulatory, and Medical Affairs to oversee trials.

Education

MD (or equivalent medical degree)

Board certification and clinical practice in cardiology

Proven ability to influence and lead cross-functional teams

Experience leading late-stage development or regulatory submissions

Strong understanding of cardiovascular trial designs and endpoints

Job description

Kardigan, Inc. is seeking a Vice President, Clinical Development to lead the Danicamtiv program. This role demands an MD or equivalent, with extensive experience directing clinical development in cardiology-focused biotechnology/pharmaceutical settings.

You will shape strategy, oversee protocol design, drive regulatory interactions, and mentor MDs within a high-growth biotech environment. You will liaise with the CMO, CEO, and executive team, present study progress, and represent Kardigan at