Oncology Clinical Development Medical Director

C4 Therapeutics, Inc.; Massachusetts; Hybrid; USD 231,000 - 255,000; Full time

Job summary

C4 Therapeutics, Inc. in Watertown, MA, is seeking an Associate Medical Director to guide clinical programs from early development through regulatory interactions, collaborating with cross-functional teams to drive study design and execution.

The role requires an MD with at least one year of clinical research in pharma/CRO/academia, exceptional scientific communication, and strong interpersonal skills to engage investigators, health authorities, and KOLs.

Qualifications

• MD with at least one year of clinical research experience in pharma, CRO, or academia.
• Ability to balance strategic vision with hands-on execution in a fast-paced matrix environment.
• Exceptional scientific communication and stakeholder engagement.

Responsibilities

• Drive development programs with cross-functional teams, refining oncology protocols from Phase I through pivotal studies.
• Collaborate with clinical operations, regulatory affairs, and biostatistics on study design and strategy.
• Serve as medical monitor for trials, ensuring safety and data quality; address issues promptly.
• Guide recruitment, trial conduct, dose escalation, and early signals of activity per trial stage.
• Assess safety information in collaboration with Pharmacovigilance to ensure patient safety.
• Develop relationships with key opinion leaders, investigators, and clinical trial sites.
• Assist in preparing global regulatory filings (IBs, INDs, CTAs, NDAs) with Senior Medical Director.
• Support site initiation visits and investigator meetings to foster collaboration.
• Represent C4T with the scientific community and contribute to publication plans.

Skills

MD

Clinical research

Scientific communication

Interpersonal skills

Analytical thinking

Education

MD or international equivalent

Job description

C4 Therapeutics, Inc. in Watertown, MA, is seeking an Associate Medical Director to guide clinical programs from early development through regulatory interactions, collaborating with cross-functional teams to drive study design and execution.

The role requires an MD with at least one year of clinical research in pharma/CRO/academia, exceptional scientific communication, and strong interpersonal skills to engage investigators, health authorities, and KOLs.