Oncology Asset Lead, Immunotherapy Programs

Astellas Pharma; Northbrook (IL); Hybrid; USD 228,000 - 326,000; Full time

Benefits offered by this job

Hybrid work model

Remote work in US

Global role with international scope

Job summary

Astellas Pharma in Northbrook, IL, is seeking a passionate drug developer and asset leader to drive late preclinical through life cycle management for immunotherapy programs (T cell engagers, ADCs, iADCs). This global role leads a matrix team and partners across EU, US and JP with hybrid/remote flexibility.

The Asset Lead oversees strategy, governance, and budget for multi-asset development, requiring a strong scientific background and business acumen to maximize asset value.

Qualifications

• A minimum of a bachelor’s degree in the sciences or pharmaceutical sciences and 10 years’ experience in drug development team leadership in pharmaceuticals, biopharmaceuticals, or biotechnology.
• Demonstrated success leading the development of asset(s) in the early development space (through clinical PoC) preferable in immunotherapy or cell therapy.
• Demonstrable experience leading IND/IMPD, NDA/MAA/BLA, or FDA Advisory Committee preparation or other CDE/PMDA/EMA meetings, or similar responsibilities.

Responsibilities

• Defines the individual brand / asset strategy with partner Global Strategic Brand Leads (GSBL). Leads the development of the program and portfolio vision, provides strategic direction and executional oversight to asset team(s) translating strategies into a comprehensive global development and registrational plan aligned with the corporate strategic plan.
• In terms of primary programs they support, be the point of accountability for program development vision and strategy and for the execution of program deliverables and day-to-day decision making for the asset(s) in partnership with the assigned GSBL.
• Accountable for leading a cross-functional asset team(s) in accordance with the E2E model to advance one or more assets from preclinical candidate nomination through clinical development, global/local regulatory submissions, and approval.
• Effectively communicates with executive leadership through relevant Governance Committees and responsible for the approval of the program and or project plans on behalf of the asset team.
• Develops clear, prospective Go/No-Go decision points and continually validates the viability of the program ensuring development plans maximize the value of the asset.
• Accountable for effective leadership within a matrix environment for assigned asset(s), implements, and ensures key development, life cycle management milestones, and budget goals for assigned projects/programs are met.
• Actively manages issues and risks and proactively identifies alternative strategies in collaboration with Asset Team representatives.
• Ensures the programs have adequate resources and technical expertise to meet the strategic objectives.
• Partners to develop a joint global strategy for co-development programs, representing Astellas’ position and minimizing escalation amongst the partners.
• Guides and mentors asset team members, champions the global asset team model and ensures team health and effectiveness.

Skills

Drug development leadership

Immunotherapy experience

IND/IMPD/NDA/FDA meetings

Education

Bachelor's degree in sciences

Doctoral or advanced degree preferable

Job description

Astellas Pharma in Northbrook, IL, is seeking a passionate drug developer and asset leader to drive late preclinical through life cycle management for immunotherapy programs (T cell engagers, ADCs, iADCs). This global role leads a matrix team and partners across EU, US and JP with hybrid/remote flexibility.

The Asset Lead oversees strategy, governance, and budget for multi-asset development, requiring a strong scientific background and business acumen to maximize asset value.