Oligonucleotide Therapeutics Scientist, RNAi Discovery

R&D Partners; South San Francisco (CA); On-site; USD 60,000 - 65,000; Full time

Benefits offered by this job

Medical insurance

401k

EAP

Disability insurance

Weekly payroll

Timecard approval

Job summary

R&D Partners is seeking an Oligonucleotide Scientist to join a biotechnology client’s Protein Sciences department in South San Francisco, CA. This 12-month contract role focuses on oligonucleotide discovery and synthesis to support an RNAi biology program and other therapeutics efforts.

The candidate will work in a collaborative chemistry team, contribute to literature reviews, and help deliver accelerated progression of oligonucleotide compounds through preclinical stages.

Qualifications

• BS/MS in Organic Chemistry or related discipline.
• Hands-on experience in oligonucleotide synthesis using automated oligo synthesizers, purification and characterization using HPLC and MS.

Responsibilities

• Work in an oligonucleotide therapeutic drug discovery lab interfacing across neuroscience, immunology and oncology.
• Perform literature reviews and execute nucleic acid chemistry plans; coordinate data.
• Establish methods for scaled-up synthesis of lead molecules and coordinate material delivery for preclinical studies.
• Maintain lab productivity to meet timelines for in vitro and in vivo studies.
• Collaborate with scientists to maintain lab equipment (oligo synthesizers, HPLC, desalting units).
• Support development of comprehensive therapeutic discovery strategy across therapeutic areas.

Skills

Oligonucleotide synthesis

Automated oligo synthesizers

HPLC

Mass spectrometry

RNAi therapeutics

Communication

Education

BS/MS in Organic Chemistry

Tools

Oligo synthesizers

HPLC

Desalting units

Mass spectrometry

Job description

R&D Partners is seeking an Oligonucleotide Scientist to join a biotechnology client’s Protein Sciences department in South San Francisco, CA. This 12-month contract role focuses on oligonucleotide discovery and synthesis to support an RNAi biology program and other therapeutics efforts.

The candidate will work in a collaborative chemistry team, contribute to literature reviews, and help deliver accelerated progression of oligonucleotide compounds through preclinical stages.