Oligonucleotide Therapeutics Scientist II

R&D Partners; South San Francisco (CA); Presencial; USD 61.000 - 81.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Medical insurance – PPO, HMO & HSA

401k plan

Employee Assistance Program

Long-term disability

Weekly payroll

Online timecard approval

Descripción de la vacante

R&D Partners in South San Francisco, CA is seeking an Oligonucleotide Scientist II to join the Protein Sciences team. The role focuses on oligonucleotide discovery and synthesis to advance our therapeutics discovery programs and interface with neuroscience, immunology and oncology efforts.

Contract position for 12 months; hands-on lab work and collaboration with chemists, with plans for scaled-up synthesis of lead molecules. Pay range $44.22-$58.93 per hour, plus benefits.

Formación

• Hands-on experience in oligonucleotide synthesis using automated oligo synthesizers.
• Purification and characterization using HPLC and mass spectrometry.
• Pharma/biotech R&D experience in RNAi therapeutics preferred.
• Knowledge of nucleic acid therapeutic modalities and modification chemistries.
• Experience in oligonucleotide delivery or bio-conjugation desirable.

Responsabilidades

• Work in an oligonucleotide therapeutic drug discovery research lab and interface across therapeutic areas to support discovery strategy.
• Troubleshoot oligonucleotide synthesis and impurity profiling where applicable.
• Collaborate with scientists to maintain lab equipment like oligo synthesizers, HPLC and desalting units.
• Propose and execute nucleic acid chemistry plans; coordinate chemistry and biology data for progression of oligonucleotide compounds.
• Establish methods for scaled-up synthesis of lead molecules and coordinate material delivery for preclinical studies.
• Maintain high laboratory productivity to meet timelines for in vitro and in vivo studies.

Conocimientos

Oligonucleotide synthesis

Laboratory troubleshooting

Educación

BS/MS in Organic Chemistry or related discipline

Herramientas

Oligo synthesizers

HPLC

Mass spectrometry

Descripción del empleo

R&D Partners in South San Francisco, CA is seeking an Oligonucleotide Scientist II to join the Protein Sciences team. The role focuses on oligonucleotide discovery and synthesis to advance our therapeutics discovery programs and interface with neuroscience, immunology and oncology efforts.

Contract position for 12 months; hands-on lab work and collaboration with chemists, with plans for scaled-up synthesis of lead molecules. Pay range $44.22-$58.93 per hour, plus benefits.