Oligonucleotide Synthesis Scientist – Drive RNA Therapeutics

Eli Lilly and Company; Indianapolis (IN); Presencial; USD 66.000 - 172.000; Jornada completa

Ventajas ofrecidas por este puesto de trabajo

Company bonus

401(k) matching

Comprehensive benefits

Descripción de la vacante

Eli Lilly and Company in Indianapolis, Indiana invites applications for a Senior Laboratory Scientist role focused on oligonucleotide synthesis in Lilly Genetic Medicines. You will operate solid-phase synthesis platforms, optimize workflows, and collaborate with discovery chemistry and analytical teams to advance lead candidates.

The position requires hands-on expertise in phosphoramidite chemistry, 2+ years in industry, and a strong track record of problem-solving in a fast-paced lab

Formación

• BS/MS in Organic Chemistry, Chemistry, Biochemistry, or related discipline.
• 2+ years of relevant industry experience.
• Authorized to work in the United States on a full-time basis.

Responsabilidades

• Synthesize therapeutic oligonucleotides (ASO, siRNA, and others) from 75-6000 μmol scales using automated solid-phase synthesizers.
• Independently troubleshoot in the laboratory to overcome synthesis challenges and improve workflows.
• Collaborate with discovery chemistry teams to understand scale-up requirements for novel molecules.

Conocimientos

Oligonucleotide synthesis

Laboratory troubleshooting

Data analysis

Documentation & record keeping

Educación

BS/MS in Organic Chemistry or related

Herramientas

AKTA Oligosynth

AKTA OP100

Mermade 12

AKTApure

TFF systems

LC-MS/UPLC

Descripción del empleo

Eli Lilly and Company in Indianapolis, Indiana invites applications for a Senior Laboratory Scientist role focused on oligonucleotide synthesis in Lilly Genetic Medicines. You will operate solid-phase synthesis platforms, optimize workflows, and collaborate with discovery chemistry and analytical teams to advance lead candidates.

The position requires hands-on expertise in phosphoramidite chemistry, 2+ years in industry, and a strong track record of problem-solving in a fast-paced lab