Oligonucleotide Manufacturing Scientist – 2nd Shift

Arrowhead Pharmaceuticals; Madison (WI); On-site; USD 60,000 - 80,000; Full time

Benefits offered by this job

Excellent benefits package

Job summary

Arrowhead Pharmaceuticals, Inc. is seeking an Associate Manufacturing Scientist I (second shift) in Madison, WI to support large-scale oligonucleotide synthesis and purification while adhering to GLP/GMP protocols.

You will operate synthesis and purification equipment, document operations, and collaborate with cross-functional teams to ensure quality, safety, and on-time production in a fast-paced environment.

Qualifications

• Bachelor's degree or equivalent in a scientific discipline.
• 0-2 years in biotech/pharma manufacturing or lab setting.
• Ability to follow detailed procedures and maintain accurate documentation.
• Strong attention to detail and quality.
• Ability to work independently and in a team, with good communication.

Responsibilities

• Follow batch records, SOPs, and work instructions to detail manufacturing steps.
• Document all operations in batch records and logbooks.
• Comply with GMP protocols.
• Operate large-scale oligonucleotide manufacturing equipment (synthesizer, purification skid, TFF, lyophilizer, reactors, meters, pumps).
• Assist with synthesis and purification of oligonucleotides; prepare reagents and mobile phases; column packing; fraction collection.
• Perform LCMS analysis of oligonucleotides and intermediates.
• Collaborate with Process Development, Analytical Development, Quality Control and QA.

Skills

GMP compliance

Batch records

Documentation

LCMS

Oligonucleotide synthesis

SOP adherence

Education

Bachelor's degree in Chemistry / Biochemistry / Biology / Chemical Engineering or related

Tools

D365 ERP

LCMS instrumentation

Chromatography

Purification systems

Job description

Arrowhead Pharmaceuticals, Inc. is seeking an Associate Manufacturing Scientist I (second shift) in Madison, WI to support large-scale oligonucleotide synthesis and purification while adhering to GLP/GMP protocols.

You will operate synthesis and purification equipment, document operations, and collaborate with cross-functional teams to ensure quality, safety, and on-time production in a fast-paced environment.