NGS Automation Scientist: Library Prep & Workflows

Integrated Resources, Inc ( IRI ); Sunnyvale (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

Integrated Resources, Inc (IRI) seeks an experienced Scientist to develop and optimize automated molecular biology workflows for next-generation sequencing (NGS) applications. The role emphasizes hands-on laboratory work, integrating complex workflows into cartridge-based consumables for closed-environment sample preparation and sequencing library construction.

The ideal candidate has 3-5 years in molecular biology or genomics, with hands-on NGS library preparation and automation experience,

Qualifications

• Bachelor's or master's degree in molecular biology, Genetics, Biochemistry, Biotechnology, Microbiology, or related scientific discipline.
• 3-5 years of relevant laboratory experience in molecular biology or genomics.
• Demonstrated hands-on experience with NGS library preparation workflows.
• Experience operating and troubleshooting laboratory automation platforms.
• Experience integrating molecular biology processes into automated workflows.
• Strong understanding of PCR, DNA extraction, nucleic acid quantification, and sequencing QC techniques.
• Experience with common genomics instrumentation and analytical software tools.
• Excellent experimental design, data analysis, documentation, and communication skills.
• Ability to independently plan and execute laboratory experiments with minimal supervision.

Responsibilities

• Execute and optimize automated nucleic acid extraction, amplification, and NGS library preparation workflows.
• Support the development of cartridge-based sample-to-library preparation systems for sequencing applications.
• Design, perform, analyze, and document experiments evaluating workflow performance, robustness, and reproducibility.
• Troubleshoot molecular biology processes integrated into automated fluidic and consumable platforms.
• Perform DNA/RNA quantification, library QC, normalization, pooling, and sequencing preparation.
• Collaborate with multidisciplinary teams including assay development, automation engineering, bioinformatics, consumables development, and systems engineering.
• Generate detailed experimental reports, protocols, and technical documentation.
• Analyze experimental data and communicate findings to project teams and leadership.
• Support technology transfer, verification, and validation activities as development projects mature.
• Maintain accurate laboratory records and ensure compliance with established laboratory practices and safety procedures.
• Contribute to continuous improvement of automated workflows and laboratory processes.

Skills

NGS library preparation

Laboratory automation

PCR

DNA extraction

Nucleic acid quantification

Experiment design

Data analysis

Documentation

Cross-functional collaboration

Safety compliance

Education

Bachelor's or Master's in molecular biology or related

Tools

NGS instrumentation

Job description

Integrated Resources, Inc (IRI) seeks an experienced Scientist to develop and optimize automated molecular biology workflows for next-generation sequencing (NGS) applications. The role emphasizes hands-on laboratory work, integrating complex workflows into cartridge-based consumables for closed-environment sample preparation and sequencing library construction.

The ideal candidate has 3-5 years in molecular biology or genomics, with hands-on NGS library preparation and automation experience,