Neurologist Principal Investigator

Irvine Clinical Research; Oakland (CA); On-site; USD 270,000 - 330,000; Full time

Job summary

Irvine Clinical Research, a West Coast leader in clinical trials, seeks a Neurologist to serve as Principal Investigator across Phase 1–3 studies in memory disorders and other neurological conditions at our California clinics.

The successful candidate will lead study teams, ensure protocol adherence, and oversee safety and patient education for trial participants, with English-language expertise essential.

Qualifications

• Valid medical license to practice in California (or license-eligible)
• Board-certified in neurology or psychiatry
• Experience working with older adults in a clinical or research setting
• Clinical research experience preferred but not required
• Fluency in professional English (spoken and written)

Responsibilities

• Lead study team as Principal Investigator or Sub-Investigator, ensuring trials are conducted safely and per protocol
• Conduct clinical intake interviews to determine medical eligibility of participants
• Educate potential participants about diseases and benefits of trial participation
• Manage participant safety and respond to adverse events promptly
• Perform cerebrospinal fluid collection (lumbar puncture) in studies
• Provide medical leadership to psychologists and study coordinators

Skills

Clinical research experience

English proficiency

Job description

Irvine Clinical Research is the largest independent clinical research site network on the West Coast. With 5 research centers in California, we are leaders in the search for new treatments in neurology, psychiatry, and obesity medicine. Our largest area of research is in Alzheimer’s Disease prevention and treatment drug trials, and our doctors were the largest contributors in the world to the most recently FDA-approved medication in Alzheimer’s Disease.

Irvine Clinical Research is hiring a Neurologist who will serve as a Principal Investigator. The physician will oversee Phase 1, 2, and 3 clinical trials of some of the most promising drugs under investigation in memory disorders and other neurological conditions. This includes next-generation disease-modifying anti-amyloid therapies in the same class as donanemab and lecanemab, anti-tau agents, and novel therapies like antisense oligonucleotides (ASOs).

Our hiring needs vary per location (Inglewood, Long Beach, Oakland, Riverside), so please indicate any preferred locations in your application.

Job Duties

• Lead study team as a Principal or Sub-Investigator, ensuring trials are conducted safely and per protocol
• Conduct clinical intake interviews to determine medical eligibility of potential study participants
• Educate potential participants about diseases and the benefits of clinical trial participation
• Manage the safety of study participants; respond appropriately to adverse events in a timely manner
• Perform cerebrospinal fluid collection (lumbar puncture) in diagnostic and therapeutic studies
• Provide medical leadership to our team of psychologists and study coordinators

Job Requirements

• Valid license to practice medicine in California (or license-eligible)
• Board-certified in neurology or psychiatry
• Experience working with older adults in a clinical or research setting
• Clinical research experience is preferred, but not required
• A command of professional spoken and written English

Hours And Compensation

This is a full-time employment position based in-person at one of our clinics (Riverside, Inglewood, Long Beach, or Oakland). There are no planned overnight or weekend hours.

The starting salary for this position is $300,000 per year. Higher salary is available with candidates meet one of the following criteria: (1) current/previous investigator in pharmaceutical clinical trials of Alzheimer’s Disease (2) superior skill in intrathecal administration and CSF collection in clinic.

The company pays for 100% of health/dental/vision individual insurance costs for eligible full-time employees. Vacation (PTO) is earned at a rate of 3 weeks per year.