Neurogenomics Tech III: CRISPR & Single-Cell

Howard Hughes Medical Institute; San Diego (CA); On-site; USD 56,000 - 71,000; Full time

Benefits offered by this job

Lab team culture

Stable funding

Scripps community

Career development

Mentorship opportunities

Publication opportunities

Competitive benefits

Job summary

Howard Hughes Medical Institute invites applications for a Research Technician III in La Jolla, CA, to support studies using genomic tools in brain development research. You’ll work on mouse handling, molecular biology, and single-cell sequencing workflows, collaborating across the Jin lab to generate high-quality data for ongoing projects.

The role offers stable, long-term opportunities, mentorship, and a chance to contribute to cutting-edge neurodevelopment research while adhering to biosafety

Qualifications

• Bachelor’s degree in life sciences required; master’s degree welcome.
• Minimum 4+ years of research in an academic lab; neuroscience experience preferred.
• Experience with mouse handling, colony management, tissue collection, genotyping, or related animal work.
• Experience with standard molecular biology techniques (DNA/RNA extraction, PCR, qPCR, gel electrophoresis, cloning).
• Experience with mammalian cell culture and sterile technique.
• Familiarity with genomics or single-cell sequencing workflows is a plus.
• Able to follow detailed protocols and maintain organized records.
• Willingness to work with mouse models and comply with animal research and biosafety policies.

Responsibilities

• Perform mouse-related lab work including handling, colony tracking, genotyping, tissue collection, and molecular analysis.
• Assist with CRISPR-based perturbation experiments and sample collection for genomic analysis.
• Carry out core molecular biology techniques (DNA/RNA extraction, PCR, qPCR, cloning, sequencing prep).
• Support single-cell genomics workflows, including nuclei/cell prep and library prep.
• Maintain mammalian cell cultures with sterile technique and monitor cell health.
• Prepare reagents and organize materials for sequencing-related experiments.
• Record procedures and results in notebooks and databases.
• Analyze data, summarize results, and troubleshoot issues affecting sample quality.

Skills

Interpersonal skills

Collaboration

Ability to follow protocols

Education

Bachelor's degree in life sciences

Master’s degree welcomed

Tools

DNA/RNA extraction

PCR

qPCR

Gel electrophoresis

Cloning

Sequencing-related sample prep

Mammalian cell culture

Job description

Howard Hughes Medical Institute invites applications for a Research Technician III in La Jolla, CA, to support studies using genomic tools in brain development research. You’ll work on mouse handling, molecular biology, and single-cell sequencing workflows, collaborating across the Jin lab to generate high-quality data for ongoing projects.

The role offers stable, long-term opportunities, mentorship, and a chance to contribute to cutting-edge neurodevelopment research while adhering to biosafety