Molecular Interactions Scientist, Biologics Discovery

Merck & Co.; Boston (MA); On-site; USD 98,000 - 154,000; Full time

Benefits offered by this job

Medical, dental, vision coverage

Other insurance benefits

Retirement benefits (401(k))

Paid holidays

Vacation

Compassionate and sick days

Job summary

Merck & Co., Inc. in Boston seeks a Scientist to join the Molecular Interactions team in Discovery Biologics.

The role involves hands-on work applying biosensor and biochemical methods to characterize protein therapeutics and targets, driving data that informs discovery and candidate selection. Responsibilities include executing binding assays (SPR/BLI), protein conjugation, and biophysical studies, with results communicated to cross-functional teams.

Qualifications

• Hands-on experience with SPR and BLI based assays on biosensor platforms.
• Understanding of protein–protein interaction analysis including affinity and kinetics.
• Experienced with data analysis using GraphPad Prism/Excel or equivalent.

Responsibilities

• Execute and optimize binding assays to evaluate affinity, kinetics, and epitope specificity.
• Perform protein conjugation and biophysical characterization studies as needed.
• Implement new technologies and communicate results to cross-functional teams.
• Support biologics discovery and candidate selection with high-quality data.
• Collaborate in a hands-on lab environment applying biosensor technologies.

Skills

SPR

BLI

Protein interactions

Data analysis tools

Education

Bachelor's degree

Master's degree

Tools

Carterra

Biacore

Octet

GraphPad Prism

Microsoft Excel

Job description

Merck & Co., Inc. in Boston seeks a Scientist to join the Molecular Interactions team in Discovery Biologics.

The role involves hands-on work applying biosensor and biochemical methods to characterize protein therapeutics and targets, driving data that informs discovery and candidate selection. Responsibilities include executing binding assays (SPR/BLI), protein conjugation, and biophysical studies, with results communicated to cross-functional teams.