Senior Scientist Biophysical Characterization Biotherapeutics

Merck; Rahway (NJ); On-site; USD 117,000 - 184,000; Full time

Job summary

Merck is seeking a Senior Scientist in biophysical/biotherapeutics characterization to advance the CMC program. You will develop and apply biophysical and particle analysis tools, collaborating across formulation, process, and device teams to strengthen drug substance and product quality.

The role offers opportunities to publish, present at conferences, and contribute to regulatory documentation while growing within a diverse, collaborative environment.

Qualifications

• PhD with 0–4 years of industry experience or MS with 4–8 years of industry experience.
• Experience in the analysis of biologics, protein/peptide stability and interactions.
• Hands-on biophysical characterization of proteins/peptides using listed techniques.
• Understanding protein aggregation mechanisms and analytical method links.
• Strong written and oral communication; ability to work cross-functionally.

Responsibilities

• Develop and implement biophysical and particle characterization tools for a biotherapeutics pipeline.
• Collaborate with process, formulation and device teams as part of the CMC development group.
• Author technical reports and regulatory documents; present data to stakeholders.
• Publish research findings and present at scientific conferences; lead project work.

Education

Ph.D. in Biophysics/ Biochemistry/ Chemistry/ Chemical Engineering/ Biomedical Engineering/ Pharmaceutical Sciences or related

M.S. in Biophysics/ Biochemistry/ Chemistry/ Chemical Engineering/ Biomedical Engineering/ Pharmaceutical Sciences or related

Tools

Circular Dichroism (CD)

Infrared Spectroscopy (IR)

Differential Scanning Calorimetry (DSC)

Analytical Ultracentrifugation (AUC)

Dynamic Light Scattering (DLS)

Job description

Merck is seeking a Senior Scientist in biophysical/biotherapeutics characterization to advance the CMC program. You will develop and apply biophysical and particle analysis tools, collaborating across formulation, process, and device teams to strengthen drug substance and product quality.

The role offers opportunities to publish, present at conferences, and contribute to regulatory documentation while growing within a diverse, collaborative environment.