Senior Scientist, Oncology Discovery & Mechanisms

Merck & Co.; Boston (MA); On-site; USD 119,000 - 188,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k)

Paid holidays

Vacation

Sick days

Job summary

Merck & Co. invites a highly qualified scientist in oncology to join the Discovery Oncology team in Boston.

The candidate will provide scientific leadership from the bench and drive the experimental strategy with deep cancer biology expertise, collaborating across multidisciplinary teams in early discovery. Key activities include leading mechanistic studies, biomarker discovery, and integration of literature to guide program direction.

Qualifications

• Demonstrated ability to work independently to create and drive experimental strategy, interpret data, troubleshoot, and define critical next steps.
• Strong experience in molecular and cellular biology techniques with emphasis on mammalian cell culture, western blot, ELISA/Mesoscale, flow cytometry, qPCR, stable cell line generation, CRISPR.
• Strong team player and experienced working with collaborative cross functional teams.

Responsibilities

• Scientific leadership through the development and implementation of multiple impactful experimental approaches to drive target validation, pathway interrogation, and mechanistic studies.
• Contribute to therapeutic mechanistic understanding, biomarker discovery, and preclinical candidate characterization.
• Monitor, review and interpret published literature to guide internal research.
• Communicate experimental findings to stakeholders.
• Leverage broad scientific expertise to influence scientific direction across programs.

Skills

Assay Development

Biology

Cancer Therapy

Cell Culture Techniques

Design of Experiments

Drug Target Identification

Flow Cytometry

Immunoassays

Independent Thinking

Mechanism of Action

Molecular Biology

Oncology

Target Discovery

Education

PhD or equivalent in oncology/biology/biochemistry/immunology

MS with 5+ years in pharma/biotech

BS with 7+ years in pharma/biotech

Job description

Merck & Co. invites a highly qualified scientist in oncology to join the Discovery Oncology team in Boston.

The candidate will provide scientific leadership from the bench and drive the experimental strategy with deep cancer biology expertise, collaborating across multidisciplinary teams in early discovery. Key activities include leading mechanistic studies, biomarker discovery, and integration of literature to guide program direction.