Molecular Imaging Radiochemist — PET Probe Innovator

US132 Guidehouse Digital, LLC; Bethesda (MD); On-site; USD 74,000 - 124,000; Full time

Benefits offered by this job

Medical, Rx, Dental & Vision Insurance

401(k) Retirement Plan

Parental Leave

Tuition Reimbursement

Job summary

Guidehouse is seeking an experienced radiochemist to support the development of PET imaging probes at our Bethesda, MD site. This full-time role involves managing routine radiotracer production, documenting processes, and collaborating with multidisciplinary teams while adhering to GMP and safety standards.

The candidate will synthesize, purify, and characterize 18F- and 89Zr-labeled probes, optimize radiolabeling methods, and help transition promising tracers to GMP production.

Qualifications

• Master’s degree; Minimum of three (3) years radiochemistry experience.
• Synthesis of PET imaging probes, especially 18F and 89Zr.
• Experience with GMP radiopharmaceutical production.
• Background in radiochemistry & analytical chemistry.

Responsibilities

• Manage routine production of PET radiotracers with thorough documentation.
• Synthesize, purify, and characterize PET imaging probes for preclinical/clinical research.
• Develop and optimize radiolabeling methods for new imaging probes.
• Produce tracers and transition promising radiotracers to GMP production.
• Collaborate with multidisciplinary teams to design and deliver imaging probes.
• Adhere to GMP, radiation safety, and institutional standards.

Skills

Radiochemistry

PET imaging probes

Automated synthesis platforms

GMP radiopharmaceutical production

Analytical chemistry

Public Trust clearance

Technical documentation

Education

Master's degree

Tools

GE TRACERlab

Trasis AllinOne

Job description

Guidehouse is seeking an experienced radiochemist to support the development of PET imaging probes at our Bethesda, MD site. This full-time role involves managing routine radiotracer production, documenting processes, and collaborating with multidisciplinary teams while adhering to GMP and safety standards.

The candidate will synthesize, purify, and characterize 18F- and 89Zr-labeled probes, optimize radiolabeling methods, and help transition promising tracers to GMP production.