MoA Scientist, Stem Cell & CAR‑T Analytics (Bench)

Genentech; South San Francisco (CA); On-site; USD 105,000 - 194,000; Full time

Benefits offered by this job

Discretionary annual bonus

Benefits package

Job summary

Genentech’s Analytical Development & Quality Control (ADQC) team is expanding to advance cell therapies. We seek a scientist to define and interrogate MoA for stem cell-derived and CAR T products, with bench work in cell culture, differentiation and flow cytometry.

Responsibilities include assay development, data documentation, SOP drafting, and regulatory support within a CMC framework. PhD or Master’s with 3+ years’ experience required.

Qualifications

• PhD in Cell Biology, Biochemistry, Bioengineering or related field; or Master’s with 3+ years’ experience.
• Bench scientist with 80%+ time spent at the bench.
• Expertise in cell biology and culture of iPSCs, MSCs or primary cells.
• Proficiency in MoA characterization including flow cytometry and molecular assays.
• Experience designing bioassays measuring function (e.g., killing, re-challenge, proliferation).

Responsibilities

• Lead MoA characterization for stem cell-derived and CAR T products.
• Execute bench experiments: cell culture, differentiation, co-culture, functional assays.
• Develop and optimize physiological and analytical assays (flow cytometry, qPCR, ELISA).
• Document data, draft SOPs, present results to cross-functional teams.
• Support regulatory activities within a CMC framework and ICH guidelines.

Skills

Cell culture

Flow cytometry

qPCR/ddPCR

ELISA

MoA analysis

Statistical analysis (GraphPad Prism/J

Education

PhD in Cell Biology/related field

MSc in Cell Biology/related field + 3+ years experience

Tools

Flow cytometer

qPCR machine

Job description

Genentech’s Analytical Development & Quality Control (ADQC) team is expanding to advance cell therapies. We seek a scientist to define and interrogate MoA for stem cell-derived and CAR T products, with bench work in cell culture, differentiation and flow cytometry.

Responsibilities include assay development, data documentation, SOP drafting, and regulatory support within a CMC framework. PhD or Master’s with 3+ years’ experience required.