MES Project Manager

Hw3 Llc; Boston (MA); On-site; USD 117,000 - 193,000; Full time

Job summary

Hw3 Llc in Boston is seeking an experienced MES Project Manager to support a major pharmaceutical manufacturing programme. This on-site role requires 3 days per week in Boston with an initial 6-month contract starting mid-November 2026.

You will coordinate dependencies across ~25 interrelated projects, track GMP change controls, equipment commissioning and qualification, SOP approvals and training, and collaborate with Manufacturing, Engineering, Quality and IT to identify risks and keep

Qualifications

• Pharmaceutical/biotech manufacturing project experience.
• Experience with MES platforms in GMP environments.
• Strong stakeholder management and on-site delivery.

Responsibilities

• Coordinate dependencies across ~25 interrelated projects with defined milestones.
• Track GMP change controls, equipment commissioning/qualification, SOP approvals, and training.
• Collaborate with Manufacturing, Engineering, Quality and IT to manage risks and blockers.
• Monitor change controls and governance to secure approvals before implementation.
• Manage dependencies across manufacturing initiatives including technology transfer.
• Maintain plans, status reports, dashboards, and provide visibility of progress and risks.
• Engage stakeholders site-wide to keep projects moving forward.

Skills

Project management

MES platforms

GMP

Change control

Stakeholder management

On-site work

Tools

MS Project

Jira

Confluence

TrackWise

Job description

• Initial 6-month contract, with potential for extension.
• Boston, MA, 3 days per week on site.
• Target start date: mid-November 2026.

We are seeking an experienced MES Project Manager to support a major pharmaceutical manufacturing programme in Boston. This role is ideal for a hands-on project manager with experience in MES, GMP environments and complex manufacturing projects.

Key Responsibilities

• Coordinate dependencies across approximately 25 interrelated projects, ensuring milestones, deliverables and responsibilities are clearly defined.
• Track critical manufacturing go-live requirements, including GMP change controls, equipment commissioning and qualification, SOP approvals and training.
• Work closely with Manufacturing, Engineering, Quality and IT teams to identify risks, resolve blockers and ensure activities are completed on schedule.
• Monitor change controls and engage with relevant governance forums to ensure approvals and actions are completed before implementation.
• Manage dependencies across multiple manufacturing initiatives, including upstream readiness and new product technology transfer activities.
• Maintain project plans, status reports and dashboards, providing clear visibility of progress, risks, timelines and potential delays.
• Proactively engage stakeholders across the site to drive accountability and keep projects moving forward.

Required Experience

• Proven project management experience within pharmaceutical or biotechnology manufacturing.
• Experience with MES platforms
• Strong understanding of GMP change control and regulated manufacturing environments.
• Knowledge of batch record dependencies and manufacturing readiness activities.
• Excellent stakeholder management and communication skills, with the ability to influence cross-functional teams without direct authority.
• A proactive, hands-on approach to project delivery, comfortable working directly with stakeholders on site.

Experience with MS Project, Jira, Confluence or TrackWise would be advantageous.