Medical Director, Early Clinical Development (Immunology)

Genentech; San Francisco (CA); On-site; USD 213,000 - 396,000; Full time

Benefits offered by this job

Relocation benefits

Job summary

Genentech’s Early Clinical Development (ECD) OMNI group is seeking a physician-scientist to drive early-phase trial design, provide medical oversight, and guide asset strategy across regulatory interactions. The role emphasizes collaboration with biomarker and safety teams, as well as engagement with external experts and regulatory bodies to shape portfolio decisions.

The candidate should hold an MD with board certification or eligibility in a related specialty, with 2+ years in

Qualifications

• MD with Board Certification or eligibility in Gastroenterology, Pulmonary, Rheumatology, Nephrology, or related specialty (M.D./Ph.D. preferred).
• 2+ years of clinical, translational, or basic research experience in immunology or inflammation.
• Understanding of early clinical drug development (Phases I–II) and GCP/ICH guidelines.
• Ability to synthesize complex biomarker and safety data to shape asset strategy.
• Strong scientific communication and collaboration across cross-functional teams.

Responsibilities

• Drive Clinical Trial Design: author early-phase protocols (Phase I/II) for NMEs.
• Serve as Medical Monitor: provide medical oversight across active trials.
• Lead Cross-Functional Strategy: represent Clinical Science on CST and PET.
• Guide Regulatory & Asset Strategy: author IND sections and briefing materials.
• Engage Global Scientific Leaders: collaborate with KOLs and advisory boards.

Skills

Clinical Expertise

Research track record

Development acumen

Strategic & collaborative mindset

Scientific communicator

Education

MD with board certification/eligibility

PhD preferred

Job description

Genentech’s Early Clinical Development (ECD) OMNI group is seeking a physician-scientist to drive early-phase trial design, provide medical oversight, and guide asset strategy across regulatory interactions. The role emphasizes collaboration with biomarker and safety teams, as well as engagement with external experts and regulatory bodies to shape portfolio decisions.

The candidate should hold an MD with board certification or eligibility in a related specialty, with 2+ years in