Medical Director, Early Clinical Development – Immunology

Genentech; South San Francisco (CA); On-site; USD 213,000 - 396,000; Full time

Benefits offered by this job

Relocation benefits

Onsite presence 3 days/week

Discretionary annual bonus

Job summary

Genentech's Early Clinical Development (ECD) OMNI group in South San Francisco seeks a physician-scientist to lead design of first-in-human and early-phase studies, oversee safety, and guide asset strategy with cross-functional teams.

Responsibilities include drafting clinical sections for INDs/IBs, coordinating with regulators, and engaging with KOLs to refine disease area strategies. Onsite presence is expected three days per week.

Qualifications

• MD with Board Certification or eligibility in gastroenterology, pulmonology, rheumatology, nephrology or related specialty.
• 2+ years of clinical, translational, or basic research experience in immunology or inflammation.
• Thorough understanding of early clinical drug development principles (Phases I–II) and GCP/ICH guidelines.

Responsibilities

• Author clinical protocols and design early-phase studies (I/II).
• Provide medical oversight, safety monitoring across active trials.
• Represent Clinical Science on CSTs and PETs with cross-functional input.
• Write IND/IB sections and health authority briefing materials.
• Collaborate with internal and external scientific leaders to refine strategies.

Skills

Clinical Expertise

Research Track Record

Development Acumen

Strategic & Collaborative Mindset

Scientific Communicator

Education

MD with Board Certification/eligibility

MD/PhD preferred

Job description

Genentech's Early Clinical Development (ECD) OMNI group in South San Francisco seeks a physician-scientist to lead design of first-in-human and early-phase studies, oversee safety, and guide asset strategy with cross-functional teams.

Responsibilities include drafting clinical sections for INDs/IBs, coordinating with regulators, and engaging with KOLs to refine disease area strategies. Onsite presence is expected three days per week.