Media & Buffer Prep Supervisor — GMP Operations Lead

Vertex Pharmaceuticals LLC; Boston (MA); On-site; USD 104,000 - 156,000; Full time

Job summary

Vertex is seeking a Media and Buffer Preparation Supervisor to lead daily media, buffer, and stock solution preparation at our Boston site. You will manage scheduling, coaching, and cross-functional partnerships to ensure GMP-ready output and readiness for scale-up and automation initiatives.

The role focuses on building a strong, accountable team, advancing process improvements, and maintaining high-quality, compliant operations in a fast-paced manufacturing environment.

Qualifications

• BS in Biochemistry, Engineering, Biology or related discipline with 7 years of industry experience or an MS with 6 years of industry experience.
• Practical industry experience in media preparation, stock solution preparation, manufacturing support, or related biopharmaceutical operations.
• Experience leading day-to-day operations in a laboratory, pilot-scale, or manufacturing support setting.
• Hands-on leadership experience with training, scheduling, troubleshooting, and team accountability.

Responsibilities

• Supervise daily media, buffer, and stock solution preparation, including scheduling, prioritization, troubleshooting, and escalation of issues.
• Lead, coach, train, and develop team members to strengthen technical skills, accountability, and operational discipline.
• Ensure consistent, accurate, and high-quality output by following standard work, procedures, and quality requirements.
• Plan staffing and resources to meet customer needs and maintain reliable operations.
• Partner with cross-functional teams to support operational readiness, scalable manufacturing practices, and business priorities.
• Drive continuous improvement, lean initiatives, and automation solutions to improve efficiency, scalability, and data visibility.
• Maintain GMP/GMP-ready compliance, safety, documentation, investigations, CAPAs, and a collaborative team environment.

Skills

Media preparation

Buffer preparation

Leadership

GMP/compliance

Process improvement

Aseptic processing

Cross-functional collaboration

Education

BS in Biochemistry/Engineering/Biology or related

MS with 6+ years experience

Tools

Automation systems

Job description

Vertex is seeking a Media and Buffer Preparation Supervisor to lead daily media, buffer, and stock solution preparation at our Boston site. You will manage scheduling, coaching, and cross-functional partnerships to ensure GMP-ready output and readiness for scale-up and automation initiatives.

The role focuses on building a strong, accountable team, advancing process improvements, and maintaining high-quality, compliant operations in a fast-paced manufacturing environment.