Mass Spectrometry Scientist

University of Kentucky; Lexington (KY); On-site; USD 75,000 - 110,000; Full time

Job summary

The Mass Spectrometry Scientist is a full-time staff position housed within the Mass Spectrometry Core under the Office of the Vice President for Research at the University of Kentucky (UK).

Reporting to the Director of the Mass Spectrometry Core, this role provides scientific data analysis, interpretation, and technical support for the Core’s mass spectrometry services, with primary emphasis on proteomics and additional support for metabolomics, at UK.

Qualifications

• Experience with proteomics data-analysis platforms such as Proteome Discoverer, DIA-NN, MSFragger/FragPipe, Skyline, MaxQuant, or related software.
• Proficiency in R, Python, or similar tools for biological data analysis and visualization.
• Experience with targeted and untargeted quantitative mass spectrometry workflows.
• Experience with high-resolution Orbitrap instrumentation.
• Experience with metabolomics or lipidomics data analysis.
• Experience in a shared research core or service environment, including communicating results to investigators with varied levels of mass spectrometry expertise.

Responsibilities

• Process, analyze, visualize, and interpret proteomics and metabolomics datasets generated through the Core.
• Assist with troubleshooting analytical methods and contribute to lab-based sample preparation as needed.
• Evaluate emerging analytical approaches for mass spectrometry data interpretation.
• Collaborate with Core scientific staff to provide reliable, reproducible, high-quality results for UK investigators.

Tools

Proteome Discoverer

DIA-NN

MSFragger/FragPipe

Skyline

MaxQuant

R

Python

Orbitrap instrumentation

Metabolomics data analysis

Job description

Required License/Registration/Certification

None

Physical Requirements

Ability to sit for long periods.

Shift

Monday-Friday, 8:00 a.m. to 5:00 p.m.

Job Summary

The Mass Spectrometry Scientist is a full-time staff position housed within the Mass Spectrometry Core under the oversight of the Office of the Vice President for Research ( VPR ). Reporting to the Director of the Mass Spectrometry Core, this position provides scientific data analysis, interpretation, and technical support for the Core’s mass spectrometry services, with primary emphasis on proteomics and additional support for metabolomics, at the University of Kentucky (UK).

The Mass Spectrometry Scientist will process, analyze, visualize, and interpret proteomics and metabolomics datasets generated through the Core. The position will also assist with troubleshooting analytical methods, contribute to laboratory-based sample preparation as needed, and evaluate emerging analytical approaches for mass spectrometry data interpretation. This scientist will work closely with other Core scientific staff to provide reliable, reproducible, and high-quality analytical results for UK investigators.

Skills / Knowledge / Abilities

Does this position have supervisory responsibilities?

Does this position have supervisory responsibilities? No

Preferred Education/Experience

• Experience with proteomics data-analysis platforms such as Proteome Discoverer, DIA -NN, MSFragger/FragPipe, Skyline, MaxQuant, or related software.
• Experience using R, Python, or similar computational tools for biological data analysis and visualization.
• Experience with targeted and untargeted quantitative mass spectrometry workflows.
• Experience with high-resolution Thermo Scientific Orbitrap instrumentation.
• Experience with metabolomics or lipidomics data analysis.
• Experience in a shared research core or service environment, including communicating results to investigators with varied levels of mass spectrometry expertise.

Deadline to Apply

Deadline to Apply 10/27/2026

Our University Community

We value the well-being of each of our employees and are dedicated to creating a healthy place for everyone to work, learn and live. In the interest of maintaining a safe and healthy environment for our students, employees, patients and visitors, the University of Kentucky is a Tobacco & Drug Free campus.

The University follows both the federal and state Constitutions as well as all applicable federal and state laws on nondiscrimination. The University provides equal opportunities for qualified persons in all aspects of institutional operations and does not discriminate on the basis of race, color, national origin, ethnic origin, religion, creed, age, physical or mental disability, veteran status, uniformed service, political belief, sex, sexual orientation, gender identity, gender expression, pregnancy, marital status, genetic information or social or economic status.

Any candidate offered a position may be required to pass pre-employment screenings as mandated by University of Kentucky Human Resources. These screenings may include a national background check and/or drug screen.

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