Mass Spectrometry Automation Scientist - Onsite SF

Spectraforce Technologies, Inc.; South San Francisco (CA); Sur place; USD 140 000 - 190 000; Plein temps

Résumé du poste

Discovery Biotherapeutics and Genetic Medicine (BGM) at client’s Bay Area site in South San Francisco seeks a Mass Spectrometry Automation Scientist. Hybrid responsibilities include production and analytical characterization of biologics and biopharmaceuticals, with emphasis on automated MS workflows and robust instrument management.

The role combines wet-lab and software automation to advance biologics programs, requiring strong communication and ability to drive decisions through MS data

Qualifications

• BS, MS or PhD in chemistry/biochemistry or related field with 7+ / 5+ / 0+ years of experience.
• Hands-on expertise with MS platforms, e.g., Waters Xevo G2-XS QToF, and MS workflows for protein characterization.
• Proficiency in data processing and bioinformatic workflows (Protein Metrics, Biosphere, Waters Connect, UNIFI).
• Experience applying LC/MS to monoclonal antibodies and biotherapeutics for sequence verification and PTMs.
• Coding experience (Python/R) and developing automated data workflows.

Responsabilités

• Conduct mass spectrometry analyses for comprehensive biologics characterization (intact, reduced, subunit).
• Maintain LC/MS equipment and troubleshoot issues.
• Design and execute production of biotherapeutic proteins with CROs; guide QA attributes and report results.
• Present findings and progress to colleagues and stakeholders.
• Collaborate with MS experts to assess new bioanalytical tech.
• Independently perform lab research and method development with minimal supervision.

Connaissances

Mass spectrometry

Automation development

Python/R coding

Data analysis

Communication

Instrument maintenance

Team collaboration

Formation

BS in chemistry/biochemistry or related

MS in chemistry/biochemistry or related

PhD in chemistry/biochemistry or related

Outils

Waters Xevo G2-XS QToF

Protein Metrics

Biosphere

Waters Connect

UNIFI

Python

R

AKTA purification

Description du poste

Discovery Biotherapeutics and Genetic Medicine (BGM) at client’s Bay Area site in South San Francisco seeks a Mass Spectrometry Automation Scientist. Hybrid responsibilities include production and analytical characterization of biologics and biopharmaceuticals, with emphasis on automated MS workflows and robust instrument management.

The role combines wet-lab and software automation to advance biologics programs, requiring strong communication and ability to drive decisions through MS data