Manager, Production

Bristol-Myers Squibb; Indianapolis (IN); On-site; USD 124,000 - 151,000; Full time

Benefits offered by this job

Wellbeing benefits

Flex Time Off

Vacation & holidays

Volunteer days

Summer hours

Global Shutdown

Job summary

RayzeBio in Indianapolis is seeking a Manager of Production to oversee day-to-day operations of the GMP radiopharmaceutical drug product manufacturing team at clinical and commercial scale. You will drive compliance, safety, and teamwork and ensure timely, quality production in line with regulatory standards.

Lead a high-performing team, manage schedules, aseptic and sterile manufacturing practices, and support investigations and CAPA programs.

Qualifications

• BS or MS in scientific field or equivalent work experience.
• At least 5 years of GMP pharmaceutical manufacturing experience; radiopharmaceutical or sterile injectables preferred.
• Experience building and leading GMP teams and ensuring compliance.

Responsibilities

• Provide in‑plant management of production personnel and ensure GMP compliance for clinical and commercial drug product manufacturing.
• Oversee daily production schedules and batch manufacturing of radiopharmaceutical injectables to meet supply demands.
• Ensure aseptic techniques and sterile manufacturing practices are followed to maintain product quality and patient safety.
• Manage cleaning and sanitization of the production clean suite and support operator qualification programs.
• Draft GMP documentation including Batch Records, SOPs, deviations, CAPAs, change controls and reports.

Skills

GMP experience

Team leadership

Communication

AI in operations

Education

BS/MS in scientific field

Job description

Life at BMS

At RayzeBio, every day is an opportunity to ignite meaningful change. As a wholly-owned subsidiary of Bristol Myers Squibb, RayzeBio blends the nimble, pioneering spirit of an emergent biotech with the global expertise and resources of a leading innovator in oncology. Our mission is to develop transformative radiopharmaceutical therapies that offer new hope for patients living with cancer. Here, you’ll join a multidisciplinary team where your ideas are valued, your expertise is amplified, and collaboration is at the heart of everything we do. From day one, expect to make an immediate impact—on our science, on our teams, and most importantly, on patients. Learn more about RayzeBio: https://careers.bms.com/rayzebio/

Summary

The Manager of Production will be responsible for the day-to-day oversight, execution, and leadership of the drug product manufacturing team engaged in the production of radiopharmaceutical injectables at clinical and commercial scale. The Manager of Production will drive a culture of compliance, safety, and teamwork in a GMP radiopharmaceutical environment while ensuring drug products are manufactured on schedule and in accordance with all applicable quality and regulatory standards. The Manager of Production will work cross functionally to meet corporate objectives and support systems related to the commercialization of RayzeBio’s programs. The Manager of Production will lead and develop a team of high performers to ensure a consistent, reliable, and timely supply of clinical and commercial drug products.

Job Responsibilities

• Provide in‑plant management of production personnel and ensure GMP compliance for clinical and commercial drug product manufacturing.
• Oversee daily production schedules and batch manufacturing of radiopharmaceutical injectables to meet supply demands.
• Ensure aseptic technique and sterile manufacturing practices are followed for the production of injectable drug product to maintain product quality and patient safety.
• Manage the cleaning and sanitization of the production clean suite.
• Support the development and implementation of a robust operator qualification program.
• Draft GMP documentation including but not limited to Batch Records, SOP’s, Forms, Deviations, CAPA’s, Change Controls and reports.
• Support investigations and implement corrective and preventative action plans.
• Monitor and manage production department KPI’s related to performance and throughput of GMP radiopharmaceutical operations.
• Ensure compliance with NRC, EH&S and US/EU GMP regulatory guidelines as required.

Education and Experience

BS or MS in scientific related field or equivalent work experience.

At least 5 years of experience in a GMP pharmaceutical manufacturing environment, with radiopharmaceutical or sterile injectable manufacturing experience preferred.

Skills and Qualification

• Highly motivated and organized professional with strong interpersonal and communication skills.
• Proven experience building and managing teams in a GMP environment.
• Excellent professional ethics, integrity, and ability to maintain confidential information.
• Applies AI to improve team execution and decision-making.

Physical Demands

While performing the duties of this job, the employee is regularly required to sit, reach with hands and arms, and talk or hear. The employee must occasionally lift and/or move up to 30 pounds. Specific vision abilities required by this job include close vision and distance vision. This is a position that requires working in a GMP cleanroom environment, wearing protective clothing, and handling of radioactive materials.

Work Environment

The noise level in the work environment is usually moderate. This is a position that requires working in a GMP cleanroom environment, wearing protective clothing, and handling of radioactive materials.

Compensation Overview

Indianapolis - RayzeBio - IN: $124,449 - $150,803 The starting pay range(s) listed above is for full‑time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits

• Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
• U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
• Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.
• U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits.

Company Information

RayzeBio and Bristol Myers Squibb RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area. For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/.

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection. Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Additional Information

We’re creating innovative medicines for patients fighting serious diseases. We’re also nurturing our own diverse team with inspiring work and challenging career options. No matter the role, each one of us makes a contribution. And that makes all the difference.