Ligand Discovery Scientist I

RepliGen Corporation

Lebanon (NH)

On-site

USD 84,000 - 121,000

Full time

14 days+

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Benefits offered by this job

Paid time off

Health/dental/vision insurance

Retirement benefits

Flexible spending accounts

Job summary

Repligen is seeking a Scientist I in the Ligand Discovery Group to identify and optimize ligands for resin platforms, applying molecular biology and discovery technologies to support product development from early research to commercialization.

The ideal candidate has strong molecular biology skills and experience with phage, yeast, or ribosomal display, plus hands-on cloning and gene-design software. Collaboration with R&D, resin development, manufacturing, and commercial teams is essential.

Qualifications

Ph.D. in Molecular Biology, Biochemistry, Biology, or a related field.
0–5 years of academic or industry experience.
Experience with phage display, yeast display, ribosomal display, or other discovery platforms.
Hands-on molecular cloning experience, including restriction enzyme-mediated cloning and Gibson Assembly.
Experience with SnapGene or similar gene design and analysis software.
Strong data analysis, problem-solving, and scientific communication skills.
Ability to work independently while contributing in a collaborative team.

Responsibilities

Design and execute experiments to discover and optimize protein-binding ligands using display technologies such as phage, yeast, or ribosomal display.
Analyze experimental data, communicate findings, and prepare technical reports and presentations for internal teams and external collaborators.
Partner with R&D, resin development, manufacturing, and commercial teams to advance projects from concept to market and support successful project outcomes.
Manage and coordinate activities for custom and catalog resin development projects, proactively driving progress and ensuring alignment across stakeholders.
Identify opportunities to improve existing workflows and implement innovative approaches that enhance discovery capabilities and accelerate project execution.
Stay informed on emerging trends, technologies, and scientific advancements in ligand discovery and protein engineering, applying new insights to advance team objectives.