Ligand Discovery Scientist I (Phage/Yeast Display)

Merck & Co.; Lebanon (NH); On-site; USD 84,000 - 121,000; Full time

Benefits offered by this job

Paid time off

Health/dental/vision

Retirement benefits

Flexible spending accounts

Job summary

Repligen’s Ligand Discovery Group is seeking a Scientist I to help identify and optimize protein-binding ligands for our resin platforms. You will apply molecular biology and discovery technologies to support product development from early research through commercialization.

The ideal candidate has strong molecular biology skills and experience with display technologies such as phage, yeast, or ribosomal display, and hands-on cloning.

Qualifications

• Ph.D. in Molecular Biology, Biochemistry, Biology, or a related field.

Responsibilities

• Design and execute experiments to discover and optimize protein-binding ligands using display technologies such as phage, yeast, or ribosomal display.
• Analyze experimental data, communicate findings, and prepare technical reports and presentations for internal teams and external collaborators.
• Partner with R&D, resin development, manufacturing, and commercial teams to advance projects from concept to market and support successful project outcomes.
• Manage and coordinate activities for custom and catalog resin development projects, proactively driving progress and ensuring alignment across stakeholders.
• Identify opportunities to improve existing workflows and implement innovative approaches that enhance discovery capabilities and accelerate project execution.
• Stay informed on emerging trends, technologies, and scientific advancements in ligand discovery and protein engineering, applying new insights to advance team objectives.

Skills

Phage display

Yeast display

Ribosomal display

Molecular cloning

Gibson Assembly

Restriction cloning

Data analysis

Scientific communication

Independent work

Collaboration

Education

Ph.D. in Molecular Biology or related field

Tools

SnapGene

Job description

Repligen’s Ligand Discovery Group is seeking a Scientist I to help identify and optimize protein-binding ligands for our resin platforms. You will apply molecular biology and discovery technologies to support product development from early research through commercialization.

The ideal candidate has strong molecular biology skills and experience with display technologies such as phage, yeast, or ribosomal display, and hands-on cloning.