Lead TIL Reprogramming for Next-Gen Immunotherapies

Weill Cornell Medicine; New York (NY); On-site; USD 160,000 - 186,000; Full time

Job summary

Weill Cornell Medicine on the Upper East Side seeks a Lead in TIL Reprogramming to oversee a focused team advancing next-generation TIL therapies. This role drives reprogramming and optimization of TILs for enhanced potency, persistence, and clinical efficacy, translating insights into scalable, IND-ready cell therapy candidates.

The successful candidate will mentor a multidisciplinary team, define target product profiles, and coordinate IND documentation while collaborating with process

Qualifications

• Doctoral-level scientist with strong leadership experience in cell therapy.
• Over 10 years of hands-on TIL biology and translational work.
• Experience designing and executing IND-enabling studies and regulatory documentation.

Responsibilities

• Lead a small multidisciplinary team focused on TIL reprogramming and optimization.
• Design strategies to enhance TIL function via media, cytokines, drugs, and gene engineering.
• Drive process innovation to improve potency, persistence, and scalability of TIL products.
• Coordinate IND documentation and contribute to CMC and pharmacology sections.
• Collaborate across process development, regulatory, clinical teams and external partners.
• Mentor team members to foster high-performance translational culture.

Skills

Team Leadership

TIL Biology

CRISPR & Gene Editing

Translational Biology

Education

Ph.D. in immunology, cancer biology, bioengineering

Tools

CRISPR

Gene Editing

Job description

Weill Cornell Medicine on the Upper East Side seeks a Lead in TIL Reprogramming to oversee a focused team advancing next-generation TIL therapies. This role drives reprogramming and optimization of TILs for enhanced potency, persistence, and clinical efficacy, translating insights into scalable, IND-ready cell therapy candidates.

The successful candidate will mentor a multidisciplinary team, define target product profiles, and coordinate IND documentation while collaborating with process