Lead Scientist, Purification & Chromatography (Pharma)

Merck & Co.; Rahway (NJ); On-site; USD 117,000 - 184,000; Full time

Job summary

Merck & Co. in Rahway, NJ seeks a Senior Scientist to lead chromatographic isolation from analytical to prep scale for APIs and impurities across small molecules, peptides, ADCs, and vaccines.

You will partner with process chemists and analytical scientists to develop efficient purification workflows, enable the development pipeline, and deliver high-purity materials for further testing and scale-up in a collaborative environment.

Qualifications

• PhD in Synthetic Chemistry, Natural Product Chemistry, Analytical Chemistry or related field.
• MS with at least 5 years in Biopharmaceutical industry.

Responsibilities

• Lead chromatographic isolation from analytical to prep scale for API and impurities.
• Collaborate with process chemists and analytical scientists to develop purification workflows.
• Deliver high-purity materials and contribute to pipeline deliverables.
• Translate R&D findings into scalable purification strategies.

Skills

Chromatography

Mass spectrometry

Analytical method development

Purification workflows

Scientific writing

External engagement

Education

Ph.D. in Synthetic Chemistry, Natural Product Chemistry, Analytical Chemistry or related field

MS with 5+ years in Biopharmaceutical industry

Tools

UPLC

PDA

MALS

SFC

MS instrumentation

Job description

Merck & Co. in Rahway, NJ seeks a Senior Scientist to lead chromatographic isolation from analytical to prep scale for APIs and impurities across small molecules, peptides, ADCs, and vaccines.

You will partner with process chemists and analytical scientists to develop efficient purification workflows, enable the development pipeline, and deliver high-purity materials for further testing and scale-up in a collaborative environment.