Senior Scientist, Pharmaceutical Purification & Chromatography

Merck; Rahway (NJ); On-site; USD 117,000 - 184,000; Full time

Job summary

Merck is seeking a Senior Scientist in Rahway, NJ, to lead chromatographic isolation from analytical to prep scale across small molecules and modalities. You will work with process chemists and analytical scientists to develop efficient purification workflows that accelerate development and deliver high-purity materials.

The role emphasizes collaboration, problem-solving, and strong scientific communication, with the aim of advancing the development pipeline and future medicines and vaccines.

Qualifications

• Ph.D. in Synthetic Chemistry, Natural product chemistry, Analytical Chemistry or a related field.
• M.S. with a minimum of 5 years of experience in the Biopharmaceutical industry.
• Experience in analytical, semi-prep/prep scale chromatography (RPLC, NPLC, SFC) technologies, instrumentation and workflows.
• Experience in mass spectrometry and its application in MS-directed chromatographic purification.
• Working knowledge of orthogonal detection technologies, including PDA, Multi-angle light scattering, charged aerosol detection etc.
• Creative problem solving in scientific R&D with track-record of translating problems to pipeline deliveries.
• External scientific engagement that may include publications, industry white papers, or presentations.
• Excellent scientific writing and verbal communication skills.

Responsibilities

• Chromatographic isolation of pharmaceutical API and impurities from analytical to prep scale.
• Collaborate with process chemists and analytical scientists to deploy purification workflows.
• Deliver high purity materials for development pipelines.
• Establish innovative purification methods to accelerate development of medicines and vaccines.

Skills

Analytical Chemistry

Analytical Method Development

Assay Development

Biopharmaceuticals

Chemical Synthesis

Chemistry

Chromatography

Mass Spectrometry (MS)

Method Development

Purification Methods

Small Molecules

Synthetic Chemistry

Synthetic Organic Chemistry

Technical Writing

UPLC

Education

Ph.D. in Synthetic Chemistry, Natural product chemistry, Analytical Chemistry or a related field

M.S. with a minimum of 5 years of experience in the Biopharmaceutical industry

Tools

RPLC

NPLC

SFC

Job description

Merck is seeking a Senior Scientist in Rahway, NJ, to lead chromatographic isolation from analytical to prep scale across small molecules and modalities. You will work with process chemists and analytical scientists to develop efficient purification workflows that accelerate development and deliver high-purity materials.

The role emphasizes collaboration, problem-solving, and strong scientific communication, with the aim of advancing the development pipeline and future medicines and vaccines.