Lead Scientist, Neuroengineering & Organoid Platforms

Open Culture; Berkeley (CA); On-site; USD 155,000 - 185,000; Full time

Benefits offered by this job

Equity

Health benefits

Flexible PTO

Job summary

Open Culture in Berkeley seeks a senior bioengineering scientist to translate cutting-edge neural models into automated Habitat workflows. You will design assays, develop disease models from iPSC-derived cultures, and support users with training and documentation.

You will collaborate with the Lab Director on culture operations, push for reproducible methods, and help scale protocols from bench to automated platforms.

Qualifications

• Assays or disease models built on iPSC-derived neural cultures or organoids with functional and molecular readouts.
• Microfluidic, perfusion-based or automated culture, or MEA electrophysiology.
• Methods others reproduce and reports people act on.

Responsibilities

• Build flagship assays: long-term potentiation, seizure response, media analysis and dose-response, standardized on Habitat.
• Take region-specific organoids and disease models from published methods to validated, automated programs with benchmarks.
• Translate bench protocols into Habitat protocols to schedule, run and audit, paired with imaging.
• Design, print and test chips and fixtures in CAD against live biology.
• Back up the Lab Director on culture operations, and write application notes and training for users.

Education

PhD in bioengineering, neuroscience or stem cell biology

Tools

CAD (Fusion 360/SolidWorks)

3D printing

Job description

Open Culture in Berkeley seeks a senior bioengineering scientist to translate cutting-edge neural models into automated Habitat workflows. You will design assays, develop disease models from iPSC-derived cultures, and support users with training and documentation.

You will collaborate with the Lab Director on culture operations, push for reproducible methods, and help scale protocols from bench to automated platforms.