Lead Scientist, Cell Line Development & GMP

BioSpace; Oxford (AL); On-site; USD 112,000 - 146,000; Full time

Job summary

Immunocore is seeking a Principal Scientist in Process Development to lead cell line development and experimental activities for protein therapeutics and GMP manufacturing. You will guide strategy, oversee DoE-based studies, and ensure regulatory alignment across CMC activities.

Collaborative leadership across QA, regulatory, and external CMOs is essential. The role emphasizes mentoring, data-driven decision making, and advancing pipeline capabilities, with a focus on compliant, scalable

Qualifications

• Leadership and communication skills
• Mammalian cell line development experience
• Understanding GMP/ICH guidelines
• Experience with tech transfer to CMOs

Responsibilities

• Drive cell line development and experimental activities
• Provide scientific/technical leadership for GMP manufacturing
• Oversee external cell line development and validation
• Transfer knowledge to contract manufacturers and QA/regulatory teams
• Maintain accurate laboratory records and data to standard
• Present findings to senior management and collaborators

Skills

Cell line development

Molecular biology

GMP knowledge

Team leadership

Bioprocess scale-up

Education

BSc/ MSc in related field

Post-doctoral experience

PhD in related discipline

Job description

Immunocore is seeking a Principal Scientist in Process Development to lead cell line development and experimental activities for protein therapeutics and GMP manufacturing. You will guide strategy, oversee DoE-based studies, and ensure regulatory alignment across CMC activities.

Collaborative leadership across QA, regulatory, and external CMOs is essential. The role emphasizes mentoring, data-driven decision making, and advancing pipeline capabilities, with a focus on compliant, scalable