Lead Research Scientist, AIR & IHC Innovation

HistoWiz; New York (NY); On-site; USD 110,000 - 170,000; Full time

Job summary

HistoWiz seeks a Scientist to provide scientific and technical leadership for the AIR and Routine IHC team. You will independently design and execute experiments, optimize assays, and guide biomarker applications, including IHC, IF, mIF, and RNAscope/HCR.

You will mentor junior scientists, lead complex projects, and contribute to expanding services and capabilities while ensuring high-quality results and adherence to quality systems.

Qualifications

• PhD in Biology or related life sciences field (or MS with substantial industry experience).
• Hands-on experience with IHC, IF, and/or ISH techniques.
• Experience optimizing assays and troubleshooting including controls.
• Strong knowledge of tissue biology, biomarkers, and experimental design.
• Experience with FFPE and/or frozen tissues from human or preclinical species.
• Ability to analyze results and troubleshoot independently.
• Familiarity with GLP/GCLP/CLIA/CAP or regulated environments is beneficial.

Responsibilities

• Lead complex AIR projects from experimental design through execution, data interpretation, and final reporting.
• Critically evaluate literature to identify antibodies, biomarkers, assays, and methodologies for IHC, IF, mIF, and RNAscope/HCR.
• Design, develop, optimize, and independently execute IHC, IF, mIF, RNAscope/HCR assays.
• Develop and optimize new protocols, assays, products, and scientific services to expand AIR and IHC capabilities.
• Troubleshoot complex technical and quality issues and collaborate with histology staff, pathologists, and other scientific personnel to ensure high-quality results and slide QC.
• Evaluate emerging technologies and methodologies and recommend their adoption when they provide scientific or operational value.
• Lead scientific discussions and project update meetings with clients.
• Provide scientific guidance and technical support to Sales and Project Management teams during project planning, execution, and troubleshooting.
• Write, review, and maintain SOPs, work instructions, protocols, and other technical documentation.
• Maintain accurate and complete experimental records and document progress in LIMS.
• Ensure procedures and documentation comply with quality standards and internal procedures.
• Contribute to continuous improvement of scientific and quality processes.

Skills

IHC

IF

RNAscope/HCR

experimental design

data interpretation

mentoring

Education

Ph.D. in Biology or related field

M.S. with substantial industry experience

Tools

Leica BOND RX

LIMS

Job description

HistoWiz seeks a Scientist to provide scientific and technical leadership for the AIR and Routine IHC team. You will independently design and execute experiments, optimize assays, and guide biomarker applications, including IHC, IF, mIF, and RNAscope/HCR.

You will mentor junior scientists, lead complex projects, and contribute to expanding services and capabilities while ensuring high-quality results and adherence to quality systems.