Lead LC-MS Scientist - Analytical Dev & QC

Actox; Carlsbad (CA); On-site; USD 140,000 - 165,000; Full time

Benefits offered by this job

Relocation assistance

Health benefits

401k plan

Dental/Vision coverage

Job summary

Actox in Carlsbad, CA is seeking a Principal Scientist – LC-MS to lead analytical development for drug substances and finished products, with hands-on LC-MS method development and validation. You will guide internal projects, manage external partnerships, and contribute to regulatory filings while maintaining strong hands-on lab involvement across R&D and QC.

The ideal candidate has a PhD with 3+ years or BS/MS with 5+ years in a GMP environment, plus experience in ICH/FDA guidelines and

Qualifications

• PhD with 3+ years in industry or BS/MS with 5+ years of relevant experience.
• Strong hands-on LC-MS experience, including method development and validation.
• Experience in GMP-regulated pharmaceutical/biotech environment.
• Understanding of ICH/FDA guidelines and phase-appropriate analytical methods.
• Experience with oligonucleotides desirable; proteins/peptides also of interest.
• Strong project management, communication, and problem-solving skills.

Responsibilities

• Lead analytical development and QC activities supporting drug substance and finished drug products.
• Develop, optimize, and validate LC-MS and other analytical methods.
• Manage internal projects and external analytical partnerships.
• Oversee release testing, stability studies, and analytical investigations.
• Contribute to regulatory submissions, including INDs, IMPDs, and CMC documentation.
• Work across R&D and routine QC with hands-on lab involvement.

Skills

LC-MS experience

Project management

Communication

Problem solving

Education

PhD with 3+ years

BS/MS with 5+ years

Tools

LC-MS instrumentation

Job description

Actox in Carlsbad, CA is seeking a Principal Scientist – LC-MS to lead analytical development for drug substances and finished products, with hands-on LC-MS method development and validation. You will guide internal projects, manage external partnerships, and contribute to regulatory filings while maintaining strong hands-on lab involvement across R&D and QC.

The ideal candidate has a PhD with 3+ years or BS/MS with 5+ years in a GMP environment, plus experience in ICH/FDA guidelines and