Lead LC-MS Clinical Assay Scientist

University of Rochester Medicine; West Henrietta (NY); On-site; USD 64,000 - 96,000; Full time

Job summary

The University of Rochester Medicine invites applications for a Sr Research Specialist to serve as the laboratory's senior scientific and technical expert in LC-MS, assay development, and emerging analytical technologies. You will lead development, validation, implementation, and optimization of clinical LC-MS assays and provide technical leadership for laboratory-developed tests.

You will collaborate with laboratory leadership, clinicians, scientists, and external partners to expand testing

Qualifications

• Bachelor's degree and 5 years of related work experience involving direct assistance to researchers required
• Master's degree preferred
• PhD preferred
• Or equivalent combination of education and experience
• Extensive hands-on experience with LC-MS/MS-based analytical platforms, including assay development, validation, optimization, troubleshooting, and implementation. Experience with both small molecules and protein/peptide analyses preferred

Responsibilities

• Lead the development, validation, implementation, optimization, and lifecycle management of clinical assays and laboratory-developed tests on LC-MS/MS, including experimental design, data analysis, interpretation of results, and transition into clinical operations.
• Ensure compliance with applicable regulatory and accreditation requirements, including CAP, CLIA, FDA, New York State Department of Health, and other standards governing clinical laboratory testing.
• Evaluate, implement, and support new instrumentation, analytical technologies, and testing platforms to advance laboratory capabilities, quality, efficiency, and strategic growth initiatives.
• Serve as the laboratory's technical expert in LCMS and related analytical technologies, providing advanced troubleshooting and resolution of complex assay, instrumentation, and operational issues.
• Support the development of technical procedures, validation plans, training materials, and other documentation necessary to support assay implementation, regulatory compliance, and laboratory operations.
• Collaborate with laboratory leadership, clinicians, scientists, and external partners to support innovation initiatives, new test development, scientific publications, grant applications, and strategic technology planning.

Skills

LC-MS/MS

Assay development

Troubleshooting

Team collaboration

Education

Bachelor's degree

Master's degree

PhD

Equivalent education and experience

Tools

LC-MS/MS instrumentation

Job description

The University of Rochester Medicine invites applications for a Sr Research Specialist to serve as the laboratory's senior scientific and technical expert in LC-MS, assay development, and emerging analytical technologies. You will lead development, validation, implementation, and optimization of clinical LC-MS assays and provide technical leadership for laboratory-developed tests.

You will collaborate with laboratory leadership, clinicians, scientists, and external partners to expand testing