Lead Computational Chemist, Structure‑Based Drug Design

Cogent Biosciences; Boulder (CO); On-site; USD 165,000 - 190,000; Full time

Benefits offered by this job

100% medical, dental, and vision premiums covered

401(k) match with immediate vesting

Generous paid time off

Paid parental leave

Tuition reimbursement

Job summary

Cogent Biosciences in Boulder, Colorado is seeking an Experienced Computational Chemist to lead in drug design and molecular modeling efforts. This role involves applying structure-based drug design methods and collaborating with project teams to optimize therapeutic leads.

The ideal candidate will have a Ph.D. in Computational Chemistry and relevant industrial experience, showcasing a strong proficiency in computational approaches and tools. The position offers a competitive salary of $165k - $190k and additional bonuses, with comprehensive benefits.

Qualifications

• 3+ years of relevant industrial experience.
• Familiarity with molecular representations and cheminformatics standards.
• Solid publication record and excellent scientific communication skills.

Responsibilities

• Apply drug design methods including docking and modeling.
• Collaborate in structure-based drug design cycles.
• Present modeling insights to project teams.
• Develop computational workflows on HPC environments.
• Train and mentor colleagues on computational tools.

Skills

Structure-based design

Docking

Virtual screening

Pharmacophore modeling

Cheminformatics tools

Programming skills

Linux/UNIX

HPC frameworks

Education

Ph.D. in Computational Chemistry or related field

Tools

MOE modeling software

Spotfire

Job description

Cogent Biosciences in Boulder, Colorado is seeking an Experienced Computational Chemist to lead in drug design and molecular modeling efforts. This role involves applying structure-based drug design methods and collaborating with project teams to optimize therapeutic leads.

The ideal candidate will have a Ph.D. in Computational Chemistry and relevant industrial experience, showcasing a strong proficiency in computational approaches and tools. The position offers a competitive salary of $165k - $190k and additional bonuses, with comprehensive benefits.