Head of Computational Chemistry, Drug Discovery

Neurocrine Biosciences, Inc.; San Diego (CA); On-site; USD 218,000 - 298,000; Full time

Job summary

Neurocrine Biosciences, Inc. in San Diego seeks a senior Computational Chemistry leader to accelerate drug discovery across modalities from early discovery to clinical candidate nomination.

You will collaborate with medicinal chemistry, structural biology, pharmacology, and data science teams to inform design, potency, selectivity, and de-risk design hypotheses, while mentoring junior scientists and advancing computational capabilities.

Qualifications

• PhD/MSc/BS with extensive computational chemistry in drug discovery.
• Proven leadership experience and ability to manage scientific teams.
• Experience integrating computational chemistry in multidisciplinary drug discovery teams.

Responsibilities

• Develops and leads computational chemistry strategies for drug discovery programs.
• Leads application of modelling and AI/ML to enable compound design and optimisation.
• Collaborates with chemistries, biology, and data science to inform project decisions.

Skills

Molecular modelling

Structure-based drug design

Cheminformatics

AI/ML in drug discovery

Cloud computing

High-performance computing

Education

PhD in computational chemistry

MS in computational chemistry

BS in chemistry

Tools

Schrödinger

OpenEye

MOE

Job description

Neurocrine Biosciences, Inc. in San Diego seeks a senior Computational Chemistry leader to accelerate drug discovery across modalities from early discovery to clinical candidate nomination.

You will collaborate with medicinal chemistry, structural biology, pharmacology, and data science teams to inform design, potency, selectivity, and de-risk design hypotheses, while mentoring junior scientists and advancing computational capabilities.