Lead AAV Downstream Scientist, Early Pipeline

Novartis Group Companies; San Diego (CA); On-site; USD 120,000 - 180,000; Full time

Job summary

Novartis Group of Companies in San Diego is seeking a Principal Scientist I/II to lead downstream purification for next-generation AAV gene therapy. You will drive early-stage process development and developability, transferring knowledge to TR&D and supporting clinical transitions.

You will manage a small team, collaborate across upstream and analytical groups, and deliver innovative, cost-effective purification strategies using AKTA.

Responsibilities

• Lead downstream purification efforts for AAV gene therapy programs.
• Collaborate across upstream and analytical groups to drive process development.
• Transfer process knowledge to TR&D and support clinical transitions.
• Manage a small team and deliver cost-effective purification strategies.

Skills

Lead downstream purification

Process development

Team management

Collaboration

Tools

AKTA

Job description

Novartis Group of Companies is seeking a Principal Scientist I/II to lead downstream purification efforts for next-generation AAV gene therapy. The role focuses on early-stage process development and developability of lead candidates, with responsibility for transferring process knowledge to TR&D and supporting clinical transitions.

The candidate will manage a small team, collaborate across upstream and analytical groups, and deliver innovative, cost-effective purification strategies with AKTA