Large Scale mAbs Engineering Project Head

Scorpion Therapeutics; Pennsylvania; On-site; USD 250,000 - 350,000; Full time

Benefits offered by this job

Healthcare

Parental leave 14wks

Job summary

Scorpion Therapeutics seeks a Senior Large Scale mAbs Engineering Project Head to lead the build and commissioning of a new drug substance manufacturing facility. You will coordinate cross‑functional teams to deliver on schedule and budget, ensuring cGMP compliance and robust process definitions.

Responsibilities include CapEx management, staffing plans, risk tracking, and integration of the new asset within the existing site, while maintaining high safety and quality standards.

Qualifications

• 10+ years project management experience in pharma/biotech.
• Experience managing projects >€1B across multiple sites.
• Proven ability to lead large teams (>100 people) in matrix environments.

Responsibilities

• Lead the Large Scale mAbs project and coordinate setup of a new drug substance manufacturing building.
• Drive project through BOD, DD, Construction, Commissioning & Qualification, and Handover.
• Ensure facility/equipment are designed, installed, qualified, maintained, and validated to cGMP standards.

Skills

Project management

Leadership

Regulatory knowledge

cGMP

Multi-site

Global projects

Risk management

Stakeholder mgmt

Education

Life Sciences/Engineering/Biotech degree

Job description

Large Scale mAbs Engineering Project Head

Main Responsibilities:

• Lead the Large Scale mAbs project and coordinate setup of a new drug substance manufacturing building.
• Perform early enabling works, permitting, and constructability reviews; drive the project through BOD, DD, Construction, Commissioning & Qualification, and Handover.
• Provide overall leadership and direction to the project team; ensure facility/equipment are designed, installed qualified, maintained, and that processes are properly validated.
• Ensure Safety & Quality standards and regulatory commitments are met.
• Oversee Engineering, Automation, Maintenance, and C&Q activities.
• Ensure on-time/on-budget execution.
• Identify, track, and report project risks; implement mitigation plans.
• Ensure the delivered building meets SPE performance targets.
• Build and execute manufacturing staffing and training plans; support workforce planning.
• Support integration of the new facility within a legacy brownfield site.
• Provide manufacturing schedule for execution and ramp-up to routine operations.
• Partner with MSAT on optimal process definition for new equipment/facility to ensure robustness, product quality, and cost optimization.
• Own CapEx management and COGs optimization.

About You (Qualifications/Skills):

• Degree in Life Sciences, Engineering, or Biotechnology.
• 10+ years project management experience, including projects >€1B.
• 10+ years managing large teams (+100 people).
• 10+ years broad pharmaceutical/pharma industrial experience.
• Experience with multi-site operations, global projects, and matrix management.
• Thorough knowledge of cGMP and regulatory requirements.
• Proven ability to build high-performing teams; decisive in complex, fast-paced environments.
• Intercultural experience; excellent communication skills.
• Ability to influence and build strong relationships with internal/external partners.

Benefits (if part of the job description):

• Health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks’ gender-neutral parental leave.