Large Scale mAbs Engineering Project Head

Mass Digital Health; Framingham (MA); On-site; USD 232,500 - 335,833; Full time

Benefits offered by this job

Health insurance

Parental leave (14 weeks)

Global exposure

Job summary

Sanofi Inc. is seeking an Engineering Project Head to lead the Large Scale mAbs project across a manufacturing facility setup. The role coordinates early enabling works, permitting, and constructability reviews, progressing through BOD, DD, Construction, Commissioning and Qualification and Handover.

You will lead Engineering, Automation, Maintenance and C&Q activities with cross-functional teams, ensuring safety, regulatory compliance, and on-time, on-budget delivery in a global context.

Qualifications

• Degree in Life Sciences, Engineering, or Biotechnology.
• >10 years of project management experience, including large projects >€1B.
• >10 years leading large teams (over 100 people).
• Extensive pharma industry experience (>10 years) and cGMP knowledge.
• Experience in multi-site, global projects with matrix management.
• Excellent communication and intercultural collaboration.

Responsibilities

• Providing leadership and direction to the Project team for manufacturing facility design, qualification and validation.
• Ensuring Safety, Quality and Regulatory commitments are met to high standards.
• Overseeing Engineering, Automation, Maintenance and C&Q activities.
• Ensuring on-time and on-budget project execution.
• Identifying and mitigating project risks and ensuring proper reporting.
• Ensuring facility delivers against SPE targets and ramps up manufacturing.
• Supporting staffing and training plans and integration within the legacy site.
• Providing Manufacturing schedule to support project execution and ramp-up.
• Contributing to process definition for new equipment and facility to ensure quality and cost optimization.
• CapEx management and COGlS optimization with accountability for efficiency.

Skills

Project management

Team leadership

Communication skills

Influencing

Intercultural experience

Regulatory knowledge

Education

Degree in Life Sciences, Engineering, or Biotechnology

Job description

Job title: Large Scale mAbs Engineering Project Head

Location: Swiftwater, PA Swiftwater, PA or Framingham, MA

About the Job

The Engineering Project Head will lead the Large Scale mAbs project and be responsible for coordinating all activities associated with the setup of the new drug substance manufacturing building. The Project lead will be responsible for early enabling works, permitting, and constructability reviews before taking the project through BOD, DD, Construction, Commissioning and Qualification and Handover. He/she represents the Global Engineering in the overall project, working in very close collaboration with the Site team. Join a global network that powers how Sanofi delivers — seamlessly, purposefully, and at scale. In Manufacturing & Supply, you’ll help reimagine how life‑changing treatments reach people everywhere, faster.

About Sanofi

We’re an R&D‑driven, AI‑powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system — and innovative pipeline — enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main Responsibilities

• Providing overall leadership and direction to the Project team, ensuring the manufacturing facility and equipment are properly designed, installed, qualified, maintained, and processes properly validated.
• Ensuring all Safety & Quality Standards, as well as Regulatory commitments, are met with the highest standards of quality.
• Oversight of all Engineering, Automation, Maintenance and C&Q activities.
• Ensuring on‑time/on‑budget execution of the project.
• Ensuring project risks are properly identified, followed‑up and reported, and that mitigation plans are implemented.
• Ensuring the building delivered complies with the performance targets committed in the SPE.
• Building and executing Manufacturing staffing and training plans along the project execution and running operations.
• Preparing and supporting strategic workforce planning.
• Preparing and supporting proper integration of the new facility within the legacy brownfield site.
• Providing the Manufacturing schedule to support the project execution as well as the manufacturing ramp‑up until routine activities are settled.
• Contributing with MSAT to the optimal process definition for new equipment and facility to ensure process robustness, product quality and costs optimization based on the current production process analysis (equipment, organization).
• CapEx management and COGs optimization are a must and the project head is accountable to deliver the most optimum efficiency.

About You

• Degree in Life Sciences, Engineering, or Biotechnology.
• > 10 years experience in Project Management including management of large projects >€1 Billion.
• >10 years of large teams’ management experience (+100 people).
• Broad industrial experience in the pharmaceutical business (>10 years).
• Experience in multi‑site operations, global projects and matrix management.
• Thorough knowledge of cGMP and regulatory requirements.
• Demonstrated ability to build highly performing teams.
• Strive for results and ability to make decisions in a complex and high‑speed environment.
• Intercultural experience.
• Excellent communication skills.
• Ability to influence and build strong relationships with internal and external partners.

Why Choose Us

• Bring the miracles of science to life alongside a supportive, future‑focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high‑quality healthcare, prevention and wellness programs and at least 14 weeks’ gender‑neutral parental leave.
• Shape the future of medicine and vaccine delivery with cutting‑edge technology, ensuring seamless launches and a resilient global supply.
• Power industry‑leading performance by leveraging digital, data, and AI‑driven innovation – at speed and scale.
• Transform lives worldwide by delivering life‑changing treatments anywhere, anytime.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affor­mintive Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

US and Puerto Rico Residents Only

North America Applicants Only

The salary range for this position is: $232,500.00 - $335,833.33. All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs.