Lab Manager

AtlasBase; South San Francisco (CA); On-site; USD 140,000 - 190,000; Full time

Job summary

AtlasBase in South San Francisco seeks a Lab Manager to oversee biology, chemistry, and engineering labs, ensuring safe, compliant operations and access to essential equipment.

You will drive EH&S programs, manage hazardous waste and SDS, and coordinate with facilities and vendors to keep a high‑productivity environment in a fast‑growing biotech setting.

Qualifications

• Bachelor's degree in biology, chemistry, or a related field; 5-10 years of laboratory management experience.
• Strong communication and organizational skills; ability to support and guide diverse technical teams.
• Proven experience leading EH&S programs and serving as a primary compliance coordinator.
• Working knowledge of chemical handling, SDS management, and waste storage and disposal requirements.
• Familiarity with common laboratory equipment (e.g., LC/MS, centrifuges, fume hoods, glass washers, DI systems) and their maintenance.
• Ability to work effectively with internal teams, contractors, and vendors.
• Cleanroom experience preferred.
• Hands-on equipment maintenance experience, supply chain/kanban systems, and reagent preparation are pluses.
• Proficiency with computer-based systems for maintenance tracking, purchasing, SOP development, and documentation.

Responsibilities

• Oversee daily operations of biology, chemistry, and engineering laboratories, including support for cleanroom activities as needed.
• Maintain organized, safe, and compliant laboratory environments; promote best practices across all lab users.
• Ensure scientists and engineers have appropriate space, equipment, and resources to perform their work effectively.
• Manage hazardous waste programs, contracted disposal services, and maintain the SDS library.
• Serve as Atlas's Environmental Health & Safety (EH&S) lead, coordinating with external consultants, leading internal safety programs, managing inspections, and chairing monthly safety meetings.
• Oversee preventive maintenance programs, service contracts, and repairs for laboratory equipment.
• Support shared lab services, including glass wash, autoclave operations, reagent stocking, and coordination with supply chain on consumables and gases.
• Partner with facilities teams on laboratory planning, expansion, and construction initiatives.
• Report to the Senior Director of Protein Development.

Skills

Communication skills

Organizational skills

EH&S program lead

Chemical handling knowledge

PPE & lab safety

Equipment maintenance

SDS management

Supply chain knowledge

Documentation systems

Education

Bachelor's degree in biology, chemistry, or a related field

Tools

LC/MS

Centrifuges

Fume hoods

Glass washers

DI systems

Job description

Key Responsibilities

• Oversee daily operations of biology, chemistry, and engineering laboratories, including support for cleanroom activities as needed.
• Maintain organized, safe, and compliant laboratory environments; promote best practices across all lab users.
• Ensure scientists and engineers have appropriate space, equipment, and resources to perform their work effectively.
• Manage hazardous waste programs, contracted disposal services, and maintain the SDS library.
• Serve as Atlas's Environmental Health & Safety (EH&S) lead, coordinating with external consultants, leading internal safety programs, managing inspections, and chairing monthly safety meetings.
• Oversee preventive maintenance programs, service contracts, and repairs for laboratory equipment.
• Support shared lab services, including glass wash, autoclave operations, reagent stocking, and coordination with supply chain on consumables and gases.
• Partner with facilities teams on laboratory planning, expansion, and construction initiatives.
• Report to the Senior Director of Protein Development.

Qualifications

• Bachelor's degree in biology, chemistry, or a related field, with 5-10 years of laboratory management experience.
• Strong communication and organizational skills; ability to support and guide diverse technical teams.
• Proven experience leading EH&S programs and serving as a primary compliance coordinator.
• Working knowledge of chemical handling, SDS management, and waste storage and disposal requirements.
• Familiarity with common laboratory equipment (e.g., LC/MS, centrifuges, fume hoods, glass washers, DI systems) and their maintenance.
• Ability to work effectively with internal teams, contractors, and vendors.
• Cleanroom experience preferred.
• Hands-on equipment maintenance experience, supply chain/kanban systems, and reagent preparation are pluses.
• Proactive, detail-oriented approach with the ability to balance operational support and compliance.
• Proficiency with computer-based systems for maintenance tracking, purchasing, SOP development, and documentation.

Physical Demands & Work Environment

Work will be performed onsite in office and laboratory space located in South San Francisco.

Mobility: Must be able to move about the laboratory and office environment regularly. This includes standing and walking for extended periods, often up to 6-8 hours per day.

Manual Dexterity: Must have fine motor skills and steady hands to handle delicate instruments, operate laboratory equipment, pipette accurately, and perform repetitive benchwork with precision.

Lifting/Carrying: Must be able to lift and carry up to 40 pounds occasionally, such as boxes of lab supplies or equipment.

Visual Acuity: Must have sufficient visual acuity to read small print on labels, instrument displays, and computer monitors. Close vision, color vision, and the ability to adjust focus are required.

Environmental Conditions: Frequently exposed to typical laboratory conditions, including biological samples, chemicals, and reagents. Must be able to wear appropriate personal protective equipment (PPE) such as lab coats, gloves, and safety goggles as required.

About AtlasBase

AtlasBase is a fast-growing pioneer in Molecular Computing, bridging the gap between traditional IT and biotechnology. We are redefining global IT infrastructure by driving breakthroughs in both Molecular Compute and Molecular Data Storage. By commercializing synthetic DNA-based technologies at IT scale, AtlasBase delivers ultra-high-density, low-maintenance, and carbon-conscious solutions built for the explosive growth and value of the world's data. Leveraging nature's most durable medium, we provide a virtually permanent foundation that transforms how the world processes and secures its most critical information.

Originally spun out of Twist Bioscience, our team is an elite fusion of scientists, engineers, and operators dedicated to solving some of the most complex infrastructure challenges on Earth. While our work is grounded in deep science, our success depends on world-class talent across every discipline. We are seeking a Lab Manager who is ready to bring their expertise to a high-impact environment and help us build a brand-new category of technology.