Lab, Clinical Research Scientist

Castle Biosciences, Inc.; Scottsdale (AZ); On-site; USD 95,000 - 130,000; Full time

Benefits offered by this job

Bonus potential

PTO 20 days annually

Holidays 10 days

401K match up to 6%

Health plan + HSA

Job summary

Castle Biosciences Inc. is seeking a Clinical Research Scientist to work from our Scottsdale, AZ laboratory. The successful candidate will troubleshoot assays, review data, and help translate study concepts into practical protocols and data-collection plans.

Collaboration with R&D, QA, and regulatory teams is essential. The role requires strong technical proficiency, creative problem solving, and 4+ years in high-complexity laboratory settings with QA experience; oncology/digital pathology

Qualifications

• Bachelor in Life Science/ Biology/ CLS with 4–7 years’ R&D experience, or Master 3–5 yrs, or PhD 1–2 yrs.
• Demonstrated technical proficiency and collaboration.
• Min 4 years lab experience in High Complexity testing plus QA training or 2 years clinical QA.
• Experience with molecular techniques, digital imaging, multiplex immunolabeling, digital pathology, image analysis, or bioinformatics.

Responsibilities

• As a primary technical resource for assay-related troubleshooting, data review and feasibility assessments.
• Collaborate with R&D to translate ideas into practical protocols and data-collection plans.
• Review results, investigate unexpected findings, optimize workflows, develop SOPs, and support instrument verification and assay validation.
• Provide technical guidance to laboratory personnel and collaborate with cross-functional teams (R&D, QA, regulatory).
• Contribute to regulatory documentation and assay submissions when needed.

Skills

Molecular techniques

Digital imaging

Multiplex immunolabeling

Digital pathology

Image analysis

Bioinformatics

QA training

Education

Bachelor in Life Science / Biology / Clinical Laboratory Science

Advanced degree (MS/PhD) preferred

Job description

Castle Biosciences Earns \"Top Workplaces USA Award\" for Phoenix, Pittsburgh, and Friendswood!

Learn more: www.CastleBiosciences.com

Castle Biosciences Inc. is growing, and we are looking to hire a Clinical Research Scientist working from laboratory in Scottsdale, AZ, with a start date on or before November 1, 2026.

Why Castle Biosciences?

Exceptional Benefits Package:

• Excellent Annual Salary + 20% Bonus Potential


• 20 Accrued PTO Days Annually + 10 Paid Holidays


• 401K with 100% Company Match up to 6%


• 3 Health Care Plan Options + Company HSA Contribution


• Company Stock Grant Upon Hire

A DAY IN THE LIFE OF A Clinical Research Scientist

As a Clinical Research Scientist, you will serve as a primary technical resource for assay-related troubleshooting, data review, feasibility assessments, and testing questions. You will work closely with R&D when new samples, study concepts, or potential projects are introduced, helping translate those ideas into practical protocols and effective data-collection plans. A key part of the role is determining how proposed methods can be performed consistently, scaled appropriately, and ultimately incorporated into a clinical laboratory environment. This includes reviewing results, investigating unexpected findings, optimizing workflows, developing and maintaining SOPs, supporting instrument verification and assay validation activities, and providing technical guidance to laboratory personnel. You will collaborate with R&D, laboratory operations, quality, regulatory, and other cross-functional teams to ensure that studies are scientifically sound and operationally practical. You may also contribute to regulatory documentation and assay submissions, although regulatory writing is not the primary focus of the position.

REQUIREMENTS

• Bachelors in Life Science, Biology, or Clinical Laboratory Science and 4-7 years research/development experience Or Master's and 3-5 years of experience or PhD and 1-2 years of experience


• Demonstrated technical proficiency, scientific creativity, successful collaboration with others, and independent thought.


• Minimum 4 years laboratory experience in High Complexity testing plus QA training or 2 years clinical QA experience


• Experience with one or more of the following: Molecular techniques, digital imaging, multiplex immunolabeling, digital pathology, image analysis or processing, bioinformatics/computational biology

*Please see the full job description at the end of the job ad.

SCHEDULE

• Monday - Friday, exempt position, working from our Scottsdale, AZ laboratory.

WORK AUTHORIZATION

All candidates must be legally authorized to work in the United States. Currently, Castle Biosciences does not sponsor H-1B visas, OPT, or employment-related visas.

ABOUT CASTLE BIOSCIENCES INC.

At Castle, it all comes down to people. After all, disease doesn't just happen - it happens to people. We believe that disease management and treatment decisions can be better informed through a person's unique biology, which is revealed through the scientific rigor of our innovative, laboratory-developed tests. We are committed to empowering healthcare providers and patients with the goal of improved outcomes.

Every employee at Castle has an impact on patient care, and we work to ensure that everyone finds their work to be both challenging and rewarding. We behave with integrity and treat our colleagues with respect and kindness. Our culture foster an environment of trust, transparency, and collaboration. We prioritize and encourage internal growth and professional development.

Castle Biosciences is an equal opportunity employer as to all protected groups, including protected veterans and individuals with disabilities.

If you have a disability and you believe you need a reasonable accommodation in order to search for a job opening or to submit an online application, please e-mail [e-mail].

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