Junior IRB Analyst

Commonwealth of VA Careers; Charlottesville (VA); Hybrid; USD 50,000 - 60,000; Full time

Benefits offered by this job

Hybrid work schedule

Job summary

University of Virginia seeks a Junior IRB Analyst to serve as an IRB generalist within the HRPP. Under supervision, you will review and process a full spectrum of IRB submissions to ensure compliance with federal regulations and UVA policies.

This is a hybrid on-site role at UVA Charlottesville, requiring 2-3 days on campus weekly. The candidate must show strong ethics understanding, attention to detail, and ability to communicate regulatory information clearly.

Qualifications

• Education: High school diploma is required.
• Preferred: Bachelor’s degree in a health-related field.
• Experience: at least two years in research compliance or related area.

Responsibilities

• Review new protocol submissions for regulatory compliance and informed consent adequacy.
• Process continuing reviews and verify ongoing compliance.
• Apply 45 CFR 46, 21 CFR 50 & 56, ICH GCP, HIPAA, FERPA and UVA policies in evaluations.
• Determine review pathway and prepare materials for IRB meetings.
• Evaluate modification requests and communicate outcomes to researchers.

Skills

Regulatory knowledge

Regulatory communication

Organizational skills

Microsoft Office

Independent/hybrid work

Education

High school diploma

Bachelor’s degree (health/science/public health)

Tools

Microsoft Office Suite

Electronic IRB management systems

Job description

The Human Research Protection Program seeks applications for multiple Junior IRB Analysts.

The Junior IRB Analyst serves as an IRB generalist within the Human Research Protection Program (HRPP) at the University of Virginia. Under the supervision of the IRB Manager or a Senior IRB Analyst, the incumbent is responsible for reviewing and processing a full spectrum of IRB submissions to ensure compliance with federal regulations, institutional policies, and ethical standards governing the protection of human research subjects.

This is a hybrid position requiring on-site presence 2-3 days per week at the University of Virginia campus in Charlottesville, Virginia. The Junior IRB Analyst must exercise sound judgment, maintain meticulous attention to detail, and demonstrate a commitment to upholding the highest standards of human research protections.

About the Human Research Protection Program

The Human Research Protection Program (HRPP) at the University of Virginia oversees all aspects of the protection of human research subjects at UVA and affiliated sites. The HRPP administers the Institutional Review Board (IRB) and works collaboratively with investigators, sponsors, and regulatory agencies to ensure that research involving human subjects is conducted with the highest standards of safety, integrity, and ethical conduct. The HRPP is committed to fostering a research environment that supports scientific advancement while protecting the rights and welfare of all research participants.

Key Responsibilities

Initial Reviews & Continuing Reviews

• Review new protocol submissions (initial reviews) to assess regulatory compliance, risk/benefit analysis, and adequacy of informed consent documents.
• Process continuing review submissions to verify ongoing compliance, evaluate any interim findings, and confirm that approval conditions remain appropriate.
• Apply applicable federal regulations (45 CFR 46, 21 CFR Parts 50 & 56), ICH GCP guidelines, HIPAA, FERPA and UVA institutional policies when evaluating submissions.
• Determine appropriate review pathway (exempt, expedited, or full-board) and prepare summary materials for IRB committee meetings when required.

Modifications

• Evaluate modification requests to approved protocols, including amendments to study procedures, consent forms, personnel, and funding sources.
• Confirm that proposed changes do not alter the risk/benefit profile in a manner requiring additional committee review beyond the assigned pathway.
• Communicate review outcomes and required revisions to research teams in a clear, timely, and professional manner.

Reportable New Information (RNI)

• Review and process Reportable New Information submissions, including unanticipated problems involving risks to subjects or others, adverse events, and protocol deviations.
• Assess the potential impact of reported information on subject safety and ongoing approval status.
• Escalate complex or urgent RNIs to senior staff or the full IRB as warranted.

Reliance Agreements & Ceding Memos

• Process reliance (single IRB / sIRB) agreements and ceding memos in support of multi-site and collaborative research.
• Coordinate with external institutions and IRBs to obtain, execute, and document appropriate agreements for reviewing or ceding review authority.
• Maintain accurate records of all executed reliance agreements and associated protocols within the electronic IRB management system.

General IRB Operations

• Provide regulatory guidance and customer service to principal investigators, study coordinators, and research staff.
• Maintain accurate and complete records in the IRB electronic submission system(s).
• Participate in IRB committee meetings, preparing agenda items and recording meeting minutes as assigned.
• Assist with quality assurance activities, policy development, and educational outreach efforts of the HRPP.
• Stay current with evolving federal regulations, guidance documents, and best practices in human research protections.
• Perform other related duties as assigned in support of HRPP operations.

Minimum Qualifications

• Education: High school diploma
• Experience: At least two years of relevant experience. Any combination of equivalent education and experience may be considered.

Required Skills and Abilities

• Demonstrated understanding of or coursework in research ethics, human subjects research regulations, or clinical research.
• Strong written and verbal communication skills with the ability to convey complex regulatory information clearly to diverse audiences.
• Excellent organizational skills and ability to manage a high-volume, deadline-driven workload with accuracy.
• Proficiency with Microsoft Office Suite (Word, Excel, Outlook); ability to learn electronic IRB management systems.
• Ability to work independently and collaboratively in a hybrid work environment.

Preferred Qualifications

• Bachelor’s degree in a health science, life science, social science, public health, law, or closely related field.
• 1-2 years of experience in an IRB office, research compliance, or clinical research administration.
• Familiarity with federal human subjects research regulations (45 CFR 46, 21 CFR Parts 50 & 56) and the Belmont Report.
• Certified IRB Professional (CIP®) credential or eligibility to sit for the exam within 24 months of hire.
• Experience with electronic IRB management platforms (e.g., Cayuse, IRBNet, Click Commerce).
• Knowledge of single IRB (sIRB) review requirements under the NIH sIRB Policy and the Revised Common Rule.

Physical Demands

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs. Occasional attendance at evening or early-morning committee meetings may be required, as well as the ability to manage multiple concurrent assignments and shifting priorities.

The anticipated hiring range is $50,000-$60,000, commensurate with education and experience.

This is an exempt-level, benefited position. Learn more about UVA benefits .

This is a restricted position, which is dependent on funding and is contingent upon funding availability.

This position has a term limit of one year after which continued employment will depend on department need and funding.

This position is based in Charlottesville, VA, and is eligible for a hybrid schedule of 2-3 days on grounds per week, with additional on-site presence as needed, in accordance with UVA’s remote work guidelines.

To learn more about UVA and the Charlottesville area, visit UVA Life and Embark CVA .

Application review will begin after September 29, 2026.

Background checks will be conducted on all new hires prior to employment.

This position will not consider candidates who require immigration sponsorship now or in the future.

The University of Virginia is an equal opportunity employer. All interested persons are encouraged to apply, including veterans and individuals with disabilities. Learn more about UVA’s commitment to non-discrimination and equal opportunity employment .