Jr/Assistant Specialist– Molecular biology, Epigenetics, and Microscopy – Molecular & Cell Biology

1000scholars; Berkeley (CA); On-site; USD 55,000 - 70,000; Full time

Job summary

University of California, Berkeley's Molecular & Cell Biology department seeks a Junior to Assistant Specialist for work in the James Nuñez Lab, focusing on molecular biology, epigenetics, and microscopy. The candidate will tag proteins using CRISPR, perform single-particle tracking with advanced microscopy, and analyze data with statistical and computational methods.

Collaboration with Profs. Nuñez and Upadhyula will provide access to state-of-the-art facilities for molecular biology, cell

Qualifications

• Experience with CRISPR tagging in human cells.
• Familiarity with high-resolution microscopy techniques.
• Ability to analyze data with statistics and computational tools.
• Record-keeping and presenting experimental results.

Responsibilities

• Genetically tag proteins that mediate epigenetic regulation in human cells using CRISPR.
• Use single-particle tracking of tagged proteins with high-resolution microscopy.
• Evaluate experimental data with appropriate statistical and computational analyses.

Skills

CRISPR tagging

Microscopy

Data analysis

Cell culture

Tools

High-resolution microscopy

Job description

The Molecular & Cell Biology at the University of California, Berkeley seeks applications for a Junior to Assistant Specialist in the James Nunez Lab, in the areas of molecular biology, epigenetics, and microscopy.

The PI studies epigenetic mechanisms in human cell lines, particularly how DNA methylation is written and remodeled on the human genome. The position is in close collaboration with Prof. Srigokul Upadhyayula to study the dynamics of DNA methylation enzymes in living cells. The project is at the interface of molecular biology, genetics and epigenetics, and high-resolution microscopy. The candidate will work closely with current researchers in the Nuñez and Upadhyayula labs at UC Berkeley and will have access to state of the art facilities for molecular biology, cell culture, and customized high-resolution microscopy equipment.

Responsibilities:

• (1) genetically tag proteins that mediate epigenetic regulation in human cells using CRISPR technologies;
• (2) use single particle tracking of the tagged proteins using high-resolution microscopy; and
• (3) evaluate the resulting experimental data using appropriate statistical and computational analyses.

The candidate is required to maintain updated records of experiments performed, present the data to the PIs and research team members, and communicate the research findings in team meetings, conferences, and publications.