In Vivo Pharmacology Research Associate II – Flexible Hours

Monte Rosa Therapeutics, Inc.; Boston (MA); In loco; USD 80.000 - 110.000; Tempo pieno

Descrizione del lavoro

Monte Rosa Therapeutics, Inc. is seeking a Senior Research Associate I/II to support in vivo proof-of-concept studies across oncology, inflammatory disease, and autoimmune programs.

You will execute in vivo pharmacology studies to characterize activity and mechanism of action of novel compounds in an AAALAC-accredited facility. The role requires occasional evening/weekend study support, and the level will be determined by qualifications and experience.

Competenze

• BS/MS in Biology, Pharmacology, Animal Science, or related field.
• Strong hands-on experience working with laboratory animals including test-agent administration by multiple routes, blood and tissue collection, and necropsy techniques.
• Prior experience safely preparing compound formulations and performing dose calculations is required.
• Ability to work flexible hours including evenings and weekends based on study needs.
• Strong organizational skills and attention to detail to maintain accurate study records.
• Willingness to learn new laboratory and sample-processing techniques and collaborate cross-functionally.
• Experience culturing mammalian cell lines is preferred.
• Experience pharmacodynamic assays using mouse tissues (Western blotting/ELISA/MSD) is a plus but not required.
• AALAS ALAT certification preferred; LVT certification is a plus.

Mansioni

• Independently perform in vivo procedures in mice including administration routes.
• Design and conduct in vivo studies to characterize target biology and compound activity.
• Maintain accurate laboratory records and study documentation.
• Perform evening and weekend animal dosing as needed.
• Assess animal health per IACUC protocols and report concerns.
• Process time-sensitive biological samples per study requirements.
• Assist with breeding programs and cage maintenance as needed.
• Perform cell culture to support tumor studies in oncology programs.

Conoscenze

In vivo pharmacology

Animal handling

Dose calculation

Documentation

Formazione

BS/MS in Biology/Pharmacology/Animal Science or related field

Strumenti

IACUC protocols

Descrizione del lavoro

Monte Rosa Therapeutics, Inc. is seeking a Senior Research Associate I/II to support in vivo proof-of-concept studies across oncology, inflammatory disease, and autoimmune programs.

You will execute in vivo pharmacology studies to characterize activity and mechanism of action of novel compounds in an AAALAC-accredited facility. The role requires occasional evening/weekend study support, and the level will be determined by qualifications and experience.