In Vivo Oncology Scientist: Tumor Models & Dosing

100 Eli Lilly and Company; South San Francisco (CA); On-site; USD 66,000 - 172,000; Full time

Benefits offered by this job

401(k)

Pension

Vacation benefits

Medical, dental, vision benefits

Flexible benefits

Life insurance

Job summary

Lilly in South San Francisco, CA is seeking a highly skilled in vivo scientist to join the Discovery Oncology team. You will execute mouse studies, manage tumor models, and support cross-functional study leads with meticulous documentation and compliance.

The role emphasizes animal handling, dosing, necropsy, and collaboration with translational colleagues; occasional weekend coverage is required. On-site work in a fast-paced environment with strong emphasis on data quality and animal welfare.

Qualifications

• Associate degree with 5+ years in vivo experience or BS with 2+ years.
• Authorized to work in the United States on a full-time basis.
• Experience with in vivo mouse work and SOPs.

Responsibilities

• Execute mouse studies, including tumor cell implantation, dosing by standard routes (e.g., PO, IP, SQ), and basic necropsy technique.
• Build proficiency in additional techniques (e.g., IV dosing, survival surgery) with training.
• Measure and record tumor volumes, body weights, and clinical observations.
• Monitor animal health and escalated findings promptly to the study lead and veterinary staff.
• Support dosing, formulation, and necropsy for studies run by other team members, including occasional weekend coverage as needed.
• Harvest and process tumor and tissue samples at study endpoints, including sample banking for downstream analysis.
• Perform basic in vitro cell culture (maintenance, expansion, quality checks of cancer cell lines) to prepare cells and reagents for implantation studies.
• Order and track lab and office supply inventory for in vivo studies.
• Maintain compliance with IACUC-approved animal care and use protocols and all laboratory research and animal handling procedures.
• Follow good research practices, SOPs, and notebook documentation standards.
• Enter, tabulate, and summarize study data (tumor growth curves, body weight change) using established templates and present results at project team meetings.
• Contribute to a safe, efficient, compliant vivarium and lab environment.

Skills

In vivo animal handling

Dosing techniques

Experimental documentation

Strong communication

Team collaboration

Education

Associate degree in animal science or biology

BS in animal science/biology/cancer biology

Tools

LI-COR Pearl imager

FlowJo

Histology/IHC tools

Survival surgery equipment

Job description

Lilly in South San Francisco, CA is seeking a highly skilled in vivo scientist to join the Discovery Oncology team. You will execute mouse studies, manage tumor models, and support cross-functional study leads with meticulous documentation and compliance.

The role emphasizes animal handling, dosing, necropsy, and collaboration with translational colleagues; occasional weekend coverage is required. On-site work in a fast-paced environment with strong emphasis on data quality and animal welfare.