In Vivo Gene Editing Faculty — Cancer Immunotherapy Leader

Mayo Clinic International; Jacksonville (FL); Hybrid; USD 150,000 - 210,000; Full time

Job summary

The Mayo Clinic Comprehensive Cancer Center invites applications for open-rank faculty positions for Cancer In Vivo Gene Editing Investigators to expand in vivo genome engineering efforts within the PG:IT program and the Cell Therapy Discovery and Translational Science initiatives. Positions are located in Jacksonville, FL or Rochester, MN.

Ideal candidates are scientists or physicians with expertise in in vivo genome engineering and gene editing technologies applied to human cells for

Qualifications

• PhD, MD, or equivalent in genetics, molecular biology, immunology, or related field.
• Record of high-impact, peer-reviewed publications in genome editing, immune engineering, or related areas.
• Experience collaborating across disciplines, particularly with immunotherapy or CAR-T programs.
• Strong commitment to mentorship, education, and building inclusive research environments.

Responsibilities

• Provide scientific leadership in genome engineering strategies.
• Collaborate with CAR-T and translational immunotherapy teams to develop engineered immune cell platforms.
• Develop novel gene editing approaches to improve efficacy and safety in cell therapies.
• Help build scalable pipelines from discovery to early-phase clinical translation.
• Contribute to Mayo Clinic PG:IT and Cell Therapy Programs' strategic growth.

Skills

CRISPR/Cas systems

Base editing

Prime editing

Epigenome editing

RNA editing

Immune cell engineering

Education

PhD/MD/MD-PhD or equivalent

Tools

CRISPR-based genome editing tools

CAR-T manufacturing infrastructure

Job description

The Mayo Clinic Comprehensive Cancer Center invites applications for open-rank faculty positions for Cancer In Vivo Gene Editing Investigators to expand in vivo genome engineering efforts within the PG:IT program and the Cell Therapy Discovery and Translational Science initiatives. Positions are located in Jacksonville, FL or Rochester, MN.

Ideal candidates are scientists or physicians with expertise in in vivo genome engineering and gene editing technologies applied to human cells for