In Vitro Pharmacologist – CardioMetabolic Discovery (Boston)

Eli Lilly and Company; Boston (MA); On-site; USD 110,000 - 189,000; Full time

Benefits offered by this job

Bonus eligibility

401(k) plan

Pension

Job summary

Eli Lilly and Company in Boston is seeking a skilled scientist to join the CardioMetabolic Research team. You will support discovery initiatives focusing on anti-obesity therapeutics, leveraging cell culture and robust assay development to advance pipelines.

The role requires strong experience in cell-based assays, molecular readouts, and collaboration across departments to meet project goals in a fast-paced environment.

Qualifications

• B.S. in Biology, Pharmacology, Biochemistry, or related field.
• 5+ years laboratory experience in industry, academia or biotechnology.
• Experience with native cell lines, primary cells or iPSCs is a plus.

Responsibilities

• Perform aseptic cell culture using mammalian cells, including transfection and stable cell line generation.
• Develop, optimize, and execute cell-based, biochemical, and enzymatic assays (ADP-Glo, Kinase-Glo) in 96- and 384-well formats.
• Apply pharmacology concepts: concentration-response curves, binding affinity, potency, Hill slope, and in vitro efficacy.
• Operate plate readers, liquid-handling robotics, and assay automation platforms.
• Perform gene expression analysis via qPCR, western blot, and flow cytometry.

Skills

Cell culture

Transfection

Stable cell lines

Assay development

qPCR

Western blot

Flow cytometry

Kinase assays

Pharmacology concepts

Education

Bachelor's degree in Biology/related field

Master's degree (preferred)

Tools

Plate readers

Liquid-handling robotics

Assay automation platforms

HTRF

ADP-Glo / Kinase-Glo

Job description

Eli Lilly and Company in Boston is seeking a skilled scientist to join the CardioMetabolic Research team. You will support discovery initiatives focusing on anti-obesity therapeutics, leveraging cell culture and robust assay development to advance pipelines.

The role requires strong experience in cell-based assays, molecular readouts, and collaboration across departments to meet project goals in a fast-paced environment.