In Vitro Pharmacology Scientist — Metabolic Disease

Zealand Pharma; Cambridge (MA); Hybrid; USD 100,000 - 135,000; Full time

Job summary

Zealand Pharma in Cambridge, MA seeks a Scientist I/II in In Vitro Pharmacology to design, execute, and interpret biochemical, biophysical, and cell-based assays supporting SAR and mechanism-of-action studies across obesity and metabolic disease programs.

You will work hands-on with GPCR biology, automate HTS workflows, collaborate with Chemistry and in vivo groups, maintain rigorous data quality, and contribute to assay development from bench to decision-ready data.

Qualifications

• PhD/MS/BS with industry/postdoc experience depending on degree level.
• Hands-on experience in in vitro pharmacology assay development.
• Experience with GPCR biology and/or obesity/metabolic disease research.

Responsibilities

• Design, develop, optimize, and validate in vitro assays (biochemical, biophysical, cell-based) to support compound screening and mechanism-of-action studies.
• Generate, analyze, and clearly communicate pharmacological data to enable timely decisions across discovery programs.
• Contribute scientific expertise in GPCR pharmacology and metabolic disease biology to disease-relevant assays.
• Support automation, liquid handling, and HTS-enabled workflows to increase throughput and quality.
• Collaborate with Chemistry, in vivo Pharmacology, DMPK/Safety, and Formulation to align data packages with candidate needs.

Skills

GPCR pharmacology

In vitro assay development

Biochemical & biophysical assays

Cell-based assays

Data analysis & communication

Team collaboration

Education

Ph.D. in Pharmacology or related field

M.S. in life sciences

B.S./B.A. in life sciences

Tools

Automation platforms

HTS-enabled workflows

Liquid handling systems

Job description

Zealand Pharma in Cambridge, MA seeks a Scientist I/II in In Vitro Pharmacology to design, execute, and interpret biochemical, biophysical, and cell-based assays supporting SAR and mechanism-of-action studies across obesity and metabolic disease programs.

You will work hands-on with GPCR biology, automate HTS workflows, collaborate with Chemistry and in vivo groups, maintain rigorous data quality, and contribute to assay development from bench to decision-ready data.