Immuno-Oncology Bioassay Research Associate—CRISPR & Cell Lines

SystImmune; Bothell (WA); On-site; USD 60,000 - 80,000; Full time

Benefits offered by this job

Premium benefits

401(k) match

Paid time off

Holidays

Job summary

SystImmune is inviting a Research Associate I/II to join the Bioassay team in Immuno-Oncology. This hands-on role supports engineering of complex cell lines and execution of cell-based immunoassays to enable discovery and development of novel cancer therapeutics.

The ideal candidate will be a strong experimentalist with experience in genetic modification and bioassay execution in a fast-paced environment. This role is full-time onsite in Redmond, WA and will move to Bothell, WA fall 2026,

Qualifications

• BS or MS in biology-related field with relevant industry experience.
• Hands-on experience with mammalian cell culture and aseptic techniques.
• Experience with genetic modification workflows such as lentiviral transduction and CRISPR knock-ins.
• Experience performing immunoassays or flow cytometry and data analysis.
• Strong organizational skills and ability to work in a team.

Responsibilities

• Engineer stable cell lines using lentiviral transduction and CRISPR knock-ins/knock-outs.
• Analyze complex datasets, prepare technical reports, and present findings.
• Perform batch qualification of reagents and cell lines for assay consistency.
• Maintain and manipulate co-cultures of primary immune cells and engineered lines.
• Conduct functional assays with imaging, flow cytometry, and ELISA platforms.
• Develop and validate cell-based and immunoassays for drug programs.

Skills

Lentiviral transduction

CRISPR knock-ins

Cell culture techniques

Flow cytometry

Immunoassays (ELISA)

Data analysis

Team collaboration

Education

BS or MS in Biology/Immunology/Cell Biology/Bioengineering/Biochemistry

Tools

Incucyte live-cell imaging

MSD multiplex platforms

GraphPad Prism

FlowJo

Job description

SystImmune is inviting a Research Associate I/II to join the Bioassay team in Immuno-Oncology. This hands-on role supports engineering of complex cell lines and execution of cell-based immunoassays to enable discovery and development of novel cancer therapeutics.

The ideal candidate will be a strong experimentalist with experience in genetic modification and bioassay execution in a fast-paced environment. This role is full-time onsite in Redmond, WA and will move to Bothell, WA fall 2026,