Hybrid IT Systems Administrator - Cloud, Security & IAM

Twistbioscience; Portland (OR); On-site; USD 90,000 - 130,000; Full time

Job summary

Twist Bioscience is seeking an IT System Administrator to oversee, maintain, and secure our hybrid IT infrastructure across on‑prem and cloud environments for a global workforce. You will serve as a Tier 2/3 escalation point and drive automation, DR planning, and security compliance.

Responsibilities include managing Windows Server AD, SaaS integrations, IAM with SSO/MFA, PKI/NAC, backups and disaster recovery testing, and documenting processes to enable adoption of new technologies.

Qualifications

• Bachelor’s degree in IT or related field or equivalent professional experience.
• 4+ years of IT systems administration or systems engineering experience.
• Experience with automation scripts using PowerShell, Bash, Python, or similar languages.
• Strong written and verbal communication for cross‑functional projects.
• Experience with Active Directory, Azure AD, and SAML-based provisioning.
• Security knowledge including PKI, certificates, and encryption.
• Experience with networking (Cisco/Meraki), storage (NetApp), and virtualization (VMware).
• Experience in ISO 27001, ITIL/SOX/SOC, or audits.

Responsibilities

• Provide system administration ownership for third‑party apps and SaaS solutions (e.g., Atlassian, Google Workspace, MS365, Slack, Zoom).
• Administer Windows Server environments including AD, DHCP, DNS, NPS, and certificate authorities.
• Manage SaaS integrations with IAM (SSO, MFA).
• Build and monitor on‑prem data center environments (networks, hypervisors, VMs, shared storage).
• Manage infrastructure security, PKI and NAC, and internal authentication.
• Plan and test backups, disaster recovery, and business continuity processes.
• Document processes and drive adoption of new IT technologies and cloud apps.
• Manage and configure RMM or monitoring systems for IT infrastructure.
• Implement Zero Trust and UEM for hybrid/remote workforce security.
• Provide Tier 2/3 end‑user and infrastructure support for US and global users.

Skills

PowerShell

Bash

Python

Automation

Windows Server

Active Directory

SAML

Security

Education

Bachelor’s degree (IT related)

MCITP (optional)

ITIL Foundation

Tools

VMware

NetApp

Cisco Meraki

Google Workspace

MS365

Job description

Twist Bioscience is seeking an IT System Administrator to oversee, maintain, and secure our hybrid IT infrastructure across on‑prem and cloud environments for a global workforce. You will serve as a Tier 2/3 escalation point and drive automation, DR planning, and security compliance.

Responsibilities include managing Windows Server AD, SaaS integrations, IAM with SSO/MFA, PKI/NAC, backups and disaster recovery testing, and documenting processes to enable adoption of new technologies.