Hybrid Director, Pharmacokinetics & DMPK Leadership

MSD; Northern (KY); Hybrid; USD 173,000 - 273,000; Full time

Job summary

Merck invites applications for a Director, Pharmacokinetics at the West Point, PA site. The role leads the DMPK group, guiding mechanistic ADME studies across modalities to influence lead selection, FIH decisions, and portfolio strategy.

The ideal candidate has a PhD or MSci with extensive drug discovery experience, strong PK/PD knowledge, and a track record in leadership and collaboration within fast-paced teams.

Qualifications

• PhD or MSci with required years in drug discovery in pharma.
• Experience leading DMPK in drug discovery programs.
• Experience integrating preclinical ADME, PK, and pharmacology data for PK/PD modeling.
• Strong leadership and communication in cross-functional teams.
• Experience with regulatory filings is preferred.

Responsibilities

• Provide strategic scientific and operational leadership for a DMPK group.
• Lead cross-functional collaboration to deliver quality data and documentation.
• Guide in silico, in vitro, and in vivo studies to inform decision making.
• Drive talent development and mentoring of staff.
• Set future strategy and implement new technologies.

Skills

ADME knowledge

Pharmacokinetics

Drug metabolism

Leadership

Team collaboration

Communication skills

Mentoring staff

PK/PD modeling

Cross-cultural awareness

Problem solving

Education

PhD in Chemistry/Pharmaceutical Sciences or related field

MSci with 12+ years experience

Tools

Analytical instrumentation

In silico tools

PBPK modeling

Job description

Merck invites applications for a Director, Pharmacokinetics at the West Point, PA site. The role leads the DMPK group, guiding mechanistic ADME studies across modalities to influence lead selection, FIH decisions, and portfolio strategy.

The ideal candidate has a PhD or MSci with extensive drug discovery experience, strong PK/PD knowledge, and a track record in leadership and collaboration within fast-paced teams.