High-Throughput Screening Scientist for ASO Therapeutics

CAMP4 Therapeutics Corp.; Cambridge (MA); On-site; USD 85,000 - 110,000; Full time

Benefits offered by this job

Medical insurance

Dental insurance

Vision insurance

401(k) plan with company contribution

Employee Stock Purchase Program

Paid parental leave

Tuition assistance

Job summary

CAMP4 Therapeutics is seeking a Research Associate II for High-Throughput Screening in Cambridge, MA. You will execute and optimize in vitro screens, manage cell models (including iPSC-derived), and generate molecular data to support ASO discovery.

Collaboration with Discovery, Chemistry, and Data Science teams is essential, with a focus on precision and throughput. The role emphasizes automation, careful experimental design, and data-driven decisions to advance potential CNS-targeted ASO

Qualifications

• BS or MS in molecular biology, biochemistry, cell biology, bioengineering or related field.
• 3+ years with BS or 1+ year with MS; biotechnology/pharma experience preferred.
• Hands-on mammalian cell culture and cell-based assays experience.
• Molecular biology techniques including RNA isolation, qPCR, and western blotting.
• Demonstrated careful execution, thorough documentation, and reproducible results.
• Preferred experience with liquid-handling automation and high-throughput screening.
• Experience with oligonucleotide therapeutics (ASOs) a plus.

Responsibilities

• Plan and execute high-throughput in vitro screens to identify ASO candidates.
• Operate liquid-handling platforms with emphasis on accuracy and throughput.
• Culture, maintain, and manipulate various cell models including iPSC-derived cells.
• Perform RNA isolation, qPCR, dPCR, and protein-based readouts.
• Analyze screening data and communicate results to cross-functional teams.
• Develop and transfer screening assays and data quality controls.
• Collaborate with Platform, Discovery, Chemistry, and Data Science teams.
• Maintain detailed records of designs, results, inventories, and data files.

Skills

Mammalian cell culture

Cell-based assays

RNA isolation

qPCR

dPCR

Western blotting

Automation/Liquid-handling

Data analysis

Microsoft Office / GraphPad / R

Education

BS or MS in molecular biology, biochemistry, cell biology, bioengineering

Tools

Liquid-handling automation

Automation platforms

qPCR machines

dPCR instruments

iPSC-derived cell culture tools

Job description

CAMP4 Therapeutics is seeking a Research Associate II for High-Throughput Screening in Cambridge, MA. You will execute and optimize in vitro screens, manage cell models (including iPSC-derived), and generate molecular data to support ASO discovery.

Collaboration with Discovery, Chemistry, and Data Science teams is essential, with a focus on precision and throughput. The role emphasizes automation, careful experimental design, and data-driven decisions to advance potential CNS-targeted ASO